Category Archives: Fragile X

Potassium Channels and their importance in ASD

Posted on March 28, 2015 by researchinitiative

Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345917/ FULL PAPER AT LINK Abstract Autism spectrum disorders (ASDs) are characterized by impaired ability to properly implement environmental stimuli that are essential to achieve a state … Continue reading →

Posted in co-morbid, epilepsy, Fragile X, Genetics, Treatment | Leave a comment

De Novo Mutations in Epilepsy link to Autism

Posted on September 12, 2013 by researchinitiative

De novo mutations in epileptic encephalopathies http://www.nature.com Epileptic encephalopathies are a devastating group of severe childhood epilepsy disorders for which the cause is often unknown1. Here we report a screen for de novo mutations in patients with two classical epileptic … Continue reading →

Posted in Autism, co-morbid, epilepsy, Fragile X, Genetics, Immune System, Inflammation, Neurology, Physiology | Leave a comment

Exercise, Enriched Environment, BDNF and Autism

Posted on July 6, 2013 by researchinitiative

Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age American Physiological Society BETHESDA, Md. (Nov. 18, 2008) − A new study confirms that exercise can reverse the age-related decline in the production of neural stem … Continue reading →

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Antibiotic Treatment for Fragile X

Posted on April 10, 2013 by researchinitiative

Minocycline, an antibiotic, improves behavior for children with fragile X syndrome http://www.ucdmc.ucdavis.edu/publish/news/newsroom/7627 Minocycline, an older, broad-spectrum antibiotic in the tetracycline family, provides meaningful improvements as a therapeutic for children with fragile X syndrome, a study by researchers at the UC … Continue reading →

Posted in Autism, Depression, Environment, Fragile X, Genetics, Immune System, Inflammation, Neurology, Physiology, Treatment | Leave a comment

Acamprostate :Treatment for Fragile X

Posted on February 27, 2013 by researchinitiative

Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome. http://www.ncbi.nlm.nih.gov/pubmed/23436129 Department of Psychiatry, Indiana University School of Medicine, and James Whitcomb Riley Hospital for Children, Indianapolis, IN, USA Abstract RATIONALE: Fragile … Continue reading →

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Glucose Metabolism, Cytotoxic T lymphocytes and mTOR

Posted on December 27, 2012 by researchinitiative

Cellular Metabolism Arms T Cells to Battle Viruses and Tumors http://www.sciencedaily.com/releases/2012/12/121224113420.htm Dec. 24, 2012 — New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the … Continue reading →

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Top 40 Research Articles of 2012 – Autism

Posted on December 24, 2012 by researchinitiative

Top 40 Research Articles – ( 40 / 350) The research that asdresearchinitiative believes has contributed greatly to our understanding of ASD and most significantly the care of ASD children. 2012 may be seen by future generations as a breakthrough … Continue reading →

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Fragile X, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 3 Comments

Fragile X – anti-inflammatory cytokine IL-10

Posted on October 14, 2012 by researchinitiative

Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10 http://www.jneuroinflammation.com/content/9/1/238/abstract Abstract (provisional) Background Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited late-onset neurodegenerative disorder, characterized both by neurological and cognitive deficits. … Continue reading →

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Fragile X Treatment

Posted on September 20, 2012 by researchinitiative

Medication Found to be Effective in Treating Social Withdrawal in Fragile X and Potentially Autism Patients http://www.rush.edu/webapps/MEDREL/servlet/NewsRelease?id=1622 Rush University Medical Centre Press Release Investigational Compound STX209 First to Target Fragile X Core Symptom (CHICAGO) – An investigational compound that targets … Continue reading →

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Antibiotics and the Gut Microbiome

Posted on August 23, 2012 by researchinitiative

Antibiotics in early life alter the murine colonic microbiome and adiposity http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11400.html?WT.ec_id=NATURE-20120823 Antibiotics administered in low doses have been widely used as growth promoters in the agricultural industry since the 1950s, yet the mechanisms for this effect are unclear. Because … Continue reading →

Posted in Allergy, Asthma, Autism, co-morbid, Environment, Epigenetics, Fragile X, General, Gut, Immune System, Inflammation, Neurology, Physiology, Treatment | Tagged , , , , , , , , , , , , , , , | Leave a comment