Monthly Archives: July 2013

Asperger’s differs in Neurophysiology – DSMV Implications

Fresh fuel reignites Asperger’s debate 29 July 2013 BioMed Central Limited Children with Asperger’s Syndrome have different electroencephalography (EEG) patterns to children with autism, reveals a study in the open access journal BMC Medicine With distinct neurophysiology, the study … Continue reading

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Natural Killer Cells – Too much of a Good Thing.

Overactive immune response blocks itself Too much of a good thing: In case of natural killer cells less is sometimes more As part of the innate immune system natural killer cells (NK cells) play an important role in immune … Continue reading

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Epilepsy and Blood Brain Barrier Dysfunction – Retrospective 2012

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia. Abstract Astrocytes are increasingly recognized as equal partners to neurons, also contributing to neurologic disorders such as epilepsy. Activated astrocytes are a common hallmark in patients … Continue reading

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TGF beta the Root of Allergies – Is it the Root of Autism ?

Johns Hopkins Researchers Reveal Genetic Glitch at the Root of Allergies Genetic pathway also known for its role in Loeys-Dietz, Marfan syndromes Newly published research by investigators at Johns Hopkins Children’s Center and the Johns Hopkins Institute of Genetic … Continue reading

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Microbes, the Gut and How Drugs interact.

Bacterial blockade Research explains how gut microbes can inactivate cardiac drugs For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body — by either activating or inactivating specific compounds … Continue reading

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mTORC – Immune Signalling and Metabolic Programming

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T-cell fate decisions1. The activation of mTOR, which is … Continue reading

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Contactins in the neurobiology of autism.

Contactins in the neurobiology of autism. Abstract Autism is a disease of brain plasticity. Inspiring work of Willem Hendrik Gispen on neuronal plasticity has stimulated us to investigate gene defects in autism and the consequences for brain development. The … Continue reading

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Immune and Autoimmune Phenomena in ASD research

Immunological and autoimmune considerations of Autism Spectrum Disorders. Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Environment, Genetics, Gut, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Early Growth Aspects – Head, Length and Weight – Autism

Early Growth Patterns in Children with Autism. Abstract BACKGROUND:: Case-control studies have found increased head growth during the first year of life in children with autism spectrum disorder. Length and weight have not been as extensively studied, and there … Continue reading

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DSM 5 Research – Still creating Uncertainty – 36% not meet New Criteria

Comorbid psychopathology rates in children diagnosed with autism spectrum disorders according to the DSM-IV-TR and the proposed DSM-5. Objective: To investigate differences in comorbid psychopathology rates between individuals who meet criteria of Autism Spectrum Disorders (ASDs) according to DSM-5 … Continue reading

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