Monthly Archives: July 2013

Asperger’s differs in Neurophysiology – DSMV Implications

Posted on July 31, 2013 by researchinitiative

Fresh fuel reignites Asperger’s debate http://www.alphagalileo.org/ViewItem.aspx?ItemId=133311&CultureCode=en 29 July 2013 BioMed Central Limited Children with Asperger’s Syndrome have different electroencephalography (EEG) patterns to children with autism, reveals a study in the open access journal BMC Medicine With distinct neurophysiology, the study … Continue reading →

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Natural Killer Cells – Too much of a Good Thing.

Posted on July 30, 2013 by researchinitiative

Overactive immune response blocks itself http://www.helmholtz-hzi.de/en/news_events/news/view/article/complete/overactive_immune_response_blocks_itself/ Too much of a good thing: In case of natural killer cells less is sometimes more As part of the innate immune system natural killer cells (NK cells) play an important role in immune … Continue reading →

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Epilepsy and Blood Brain Barrier Dysfunction – Retrospective 2012

Posted on July 26, 2013 by researchinitiative

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia. http://www.ncbi.nlm.nih.gov/pubmed/23134496 Abstract Astrocytes are increasingly recognized as equal partners to neurons, also contributing to neurologic disorders such as epilepsy. Activated astrocytes are a common hallmark in patients … Continue reading →

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TGF beta the Root of Allergies – Is it the Root of Autism ?

Posted on July 26, 2013 by researchinitiative

Johns Hopkins Researchers Reveal Genetic Glitch at the Root of Allergies http://www.hopkinsmedicine.org/news/media/releases/johns_hopkins_researchers_reveal_genetic_glitch_at_the_root_of_allergies Genetic pathway also known for its role in Loeys-Dietz, Marfan syndromes Newly published research by investigators at Johns Hopkins Children’s Center and the Johns Hopkins Institute of Genetic … Continue reading →

Posted in Allergy, Asthma, Autism, co-morbid, Environment, Immune System, Inflammation, Neurology, Physiology, Treatment | Leave a comment

Microbes, the Gut and How Drugs interact.

Posted on July 26, 2013 by researchinitiative

Bacterial blockade http://news.harvard.edu/gazette/story/2013/07/bacterial-blockade/ Research explains how gut microbes can inactivate cardiac drugs For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body — by either activating or inactivating specific compounds … Continue reading →

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mTORC – Immune Signalling and Metabolic Programming

Posted on July 25, 2013 by researchinitiative

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function http://www.nature.com/nature/journal/v499/n7459/full/nature12297.html?WT.ec_id=NATURE-20130725 The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T-cell fate decisions1. The activation of mTOR, which is … Continue reading →

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Contactins in the neurobiology of autism.

Posted on July 24, 2013 by researchinitiative

Contactins in the neurobiology of autism. http://www.ncbi.nlm.nih.gov/pubmed/23872404 Abstract Autism is a disease of brain plasticity. Inspiring work of Willem Hendrik Gispen on neuronal plasticity has stimulated us to investigate gene defects in autism and the consequences for brain development. The … Continue reading →

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Immune and Autoimmune Phenomena in ASD research

Posted on July 24, 2013 by researchinitiative

Immunological and autoimmune considerations of Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/23867105 Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired … Continue reading →

Posted in Allergy, Asthma, Autism, co-morbid, Environment, Genetics, Gut, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Early Growth Aspects – Head, Length and Weight – Autism

Posted on July 24, 2013 by researchinitiative

Early Growth Patterns in Children with Autism. http://www.ncbi.nlm.nih.gov/pubmed/23867813 Abstract BACKGROUND:: Case-control studies have found increased head growth during the first year of life in children with autism spectrum disorder. Length and weight have not been as extensively studied, and there … Continue reading →

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DSM 5 Research – Still creating Uncertainty – 36% not meet New Criteria

Posted on July 24, 2013 by researchinitiative

Comorbid psychopathology rates in children diagnosed with autism spectrum disorders according to the DSM-IV-TR and the proposed DSM-5. http://www.ncbi.nlm.nih.gov/pubmed/23869479 Objective: To investigate differences in comorbid psychopathology rates between individuals who meet criteria of Autism Spectrum Disorders (ASDs) according to DSM-5 … Continue reading →

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