Category Archives: Physiology

Early Life Immune Activation and ASD

Perinatal Immune Activation Produces Persistent Sleep Alterations and Epileptiform Activity in Male Mice. https://www.ncbi.nlm.nih.gov/pubmed/28984294# Abstract Increasing evidence suggests a role for inflammation in neuropsychiatric conditions including autism spectrum disorder (ASD). Previous work in rodents has established that immune activation during … Continue reading

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Maternal Immune System linked to Autism outcome

Mum’s immune response could trigger social deficits for kids with autism https://sydney.edu.au/news-opinion/news/2017/10/10/mum-s-immune-response-could-trigger-social-deficits-for-kids-wit.html Unlocking autism with applied research Children with autism are more likely to show severe social symptoms if their mother had chronic asthma or allergies while pregnant, the University … Continue reading

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Startling Discovery – Immune System Affects and may Control Social Behavior

Shocking New Role Found for the Immune System: Controlling Social Interactions https://news.virginia.edu In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects … Continue reading

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Chronic Lack of Sleep – Linked to Neurological Damage – Implications for Autism ?

¬†Insomnia Linked to Damage in Brain Communication Networks https://www2.rsna.org At A Glance Twenty-three insomnia patients and 30 healthy controls were examined with diffusion tensor imaging and given questionnaires to evaluate mental status and sleep patterns. Compared to the healthy controls, … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704 ¬†Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516 ¬†Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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Maternal Care – Key to Autism

Obesity, Diabetes in Mom Increases Risk of Autism in Child http://www.jhsph.edu/news/news-releases/2016/obesity-diabetes-in-mom-increases-risk-of-autism-in-child.html New study offers new evidence that autism spectrum disorder risks may begin in utero Children born to obese women with diabetes are more than four times as likely to … Continue reading

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Maternal Antidepressant Use and Autism

Antidepressant Use During Pregnancy and the Risk of Autism Spectrum Disorder in Children. http://www.ncbi.nlm.nih.gov/pubmed/26660917 Abstract Importance: The association between the use of antidepressants during gestation and the risk of autism spectrum disorder (ASD) in children is still controversial. The etiology … Continue reading

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Autism and Industrial Pollution

Autism spectrum disorder prevalence and proximity to industrial facilities releasing arsenic, lead or mercury. http://www.ncbi.nlm.nih.gov/pubmed/26218563 Abstract Prenatal and perinatal exposures to air pollutants have been shown to adversely affect birth outcomes in offspring and may contribute to prevalence of autism … Continue reading

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Eczema and Autism – The Association

Association Between Atopic Dermatitis and Autism Spectrum Disorders: A Systematic Review. http://www.ncbi.nlm.nih.gov/pubmed/26254000 Atopic dermatitis (AD) is an allergic disorder caused by both immunological dysregulation and epidermal barrier defect. Several studies have investigated the association between AD and mental health disorders. … Continue reading

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