Monthly Archives: May 2012

Fetal Brain Injury II

Inflammation during fetal and neonatal life: implications for neurologic and neuropsychiatric disease in children and adults. http://www.ncbi.nlm.nih.gov/pubmed/22334391 Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, SwedenAbstract “Inflammation is increasingly recognized as being of both physiological … Continue reading

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Fetal Brain Injury

Models of fetal brain injury, intrauterine inflammation, and preterm birth. http://www.ncbi.nlm.nih.gov/pubmed/22380481 Department of Gynecology, Johns Hopkins University, Baltimore. Abstract “Intrauterine infection and inflammation are known risk factors for brain damage in the neonate irrespective of the gestational age. Infection-induced maternal … Continue reading

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Mast Cells and Autism – Treatment possibilities

I have previously posted work from Dr Theoharides at Tufts University Boston http://www.mastcellmaster.com/ Corticotropin-releasing hormone and extracellular mitochondria augment IgE-stimulated human mast-cell vascular endothelial growth factor release, which is inhibited by luteolin. http://www.ncbi.nlm.nih.gov/pubmed/22559745 BACKGROUND: Autism Spectrum Disorders (ASD) are neurodevelopmental … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Immune System, Inflammation, Physiology, Treatment | 1 Comment

Autism and Schizophrenia – CNV Overlaps

Association testing of copy number variants in schizophrenia and autism spectrum disorders http://www.jneurodevdisorders.com/content/4/1/15/abstract Journal of Neurodevelopmental Disorders 2012, 4:15┬ádoi:10.1186/1866-1955-4-15 Published: 30 May 2012 Abstract (provisional) Background “Autism spectrum disorders and schizophrenia have been associated with an overlapping set of copy … Continue reading

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Microglia

Nice article presented in Nature outlining some of the new knowledge in regards to Microglia. These have been the focus of research by researchers at Johns Hopkins Neuroimmunopathology Laboratory in regards to autism here … http://www.neuro.jhmi.edu/neuroimmunopath/autism.htm.Microglia: The constant gardeners Once … Continue reading

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Autism, Antioxidants and Irritability

Stanford University researchers trialling antioxidant treatment that may lower irritability and have positive effects on repetitive behaviors. Coincidentally I’d just finished this book …The Autism Revolution: Whole-Body Strategies for Making Life All It Can Be by Martha Herbert at Harvard. … Continue reading

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Autism and Autoimmune Disease – IMFAR 2012

Gene Network Analysis of Autism and Autoimmue Disorders http://imfar.confex.com/imfar/2012/webprogram/Paper11459.html J. Y. Jung1 and D. P. Wall2, (1)Harvard Medical School, Boston, MA, (2)Pathology/Center for Biomedical Informatics, Harvard Medical School, Boston, MA Background:”Autism is highly heritable, but the genetic risk factors of … Continue reading

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Autism, Schizophrenia, Epilepsy and Developmental Disorder – Genes – IMFAR 2012

Variable Phenotypic Expressivity of Specific Copy Number Variants and Single Gene Mutations in Autism and Other Neurodevelopmental Disorders http://imfar.confex.com/imfar/2012/webprogram/Paper11765.html “The objective of this literature review was to examine the variable phenotypic expression of selected DNA copy number variants (CNVs) and … Continue reading

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SFARI talks about Rats in 2011- Gut Bacteria and Autism

Just a quick link to a Simons Foundation Autism Research Initiative (SFARI) 2011 article outlining the work surrounding bacteria and the gut in Autism. http://sfari.org/news-and-opinion/news/2011/studies-implicate-gut-bacteria-in-autism “The latest research, conducted over the past several years, probes the controversial possibility that whatever … Continue reading

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…. and Rats, Propionic Acid and Autism – One more time – IMFAR 2012

Intraventricular Enteric Short Chain Fatty Acid Infusions in Rats Induce Behavioural, Neuropathological, Lipid and Epigenetic Changes Consistent with Autism B. B. Nankova1, E. LaGamma1, A. R. Taylor2, L. J. Tichenoff2 and D. F. MacFabe3, (1)Westchester Medical Centre, New York Medical … Continue reading

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