Monthly Archives: March 2014

Tom Insel Speaks about New CDC 1 in 68 Autism Prevalence

Director’s Blog: Autism Awareness: April 2014 http://www.nimh.nih.gov/about/director/2014/autism-awareness-april-2014.shtml   Autism Awareness Month arrives this year with a package of new, important research findings. Below I describe a few of these. The field is moving so rapidly that, by the end of … Continue reading

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mTOR pathway and Seizure Development

Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation. http://www.ncbi.nlm.nih.gov/pubmed/24672426 Abstract The phosphatidylinositol-3-kinase/phosphatase and tensin homolog (PTEN)-mammalian target of rapamycin (mTOR) pathway regulates a variety of neuronal functions, including cell proliferation, survival, growth, and plasticity. Dysregulation of the … Continue reading

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Chronic Early Life Stress – Implications for Autism, Anxiety and Depression

Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood http://www.cshl.edu Cold Spring Harbor, NY — In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the … Continue reading

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Paracetemol and Eczema

Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study http://www.biomedcentral.com/1471-5945/14/6/abstract Background There is a concern that allergic disease in childhood is higher than expected in Cuba. The aim of this study was to determine the risk … Continue reading

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Variable Insult Hypothesis in Autism – Neuroimmune Abnormalities

Neuro-Immune Abnormalities in Autism and Their Relationship with the Environment: A Variable Insult Model for Autism http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945747/ Full Paper at Link Abstract Autism spectrum disorder (ASD) is a heterogeneous condition affecting an individual’s ability to communicate and socialize and often … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Genetics, Gut, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

New Autism Treatment – Antianxiety Drugs

Low doses of antianxiety drugs rebalance the autistic brain www,cell.com New research in mice suggests that autism is characterized by reduced activity of inhibitory neurons and increased activity of excitatory neurons in the brain, but balance can be restored with … Continue reading

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Specific Biological Targets – New Thinking in Neuropsychiatric Disorders

What lies beneath http://links.ealert.nature.com A focus on specific biological targets rather than constellations of symptoms heralds a more scientific approach to the treatment of neuropsychiatric disorders. Full Article at Link NIH rethinks psychiatry trials Mental-health division will no longer fund … Continue reading

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Dark Chocolate, Gut Microbes and Anti-Inflammatory Compounds

The precise reason for the health benefits of dark chocolate: mystery solved http://www.acs.org Presented at a meeting of the American Chemical Society. DALLAS, March 18, 2014 — The health benefits of eating dark chocolate have been extolled for centuries, but … Continue reading

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Stress as a Psycho-Biological Mechanism – Implications for Autism ?

Stress undermines empathic abilities in men but increases them in women http://www.sissa.it/index.php/about/news/general/2774 Stressed males tend to become more self-centered and less able to distinguish their own emotions and intentions from those of other people.  For women the exact opposite is … Continue reading

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Environmental Factors, Pesticides, Viruses and Autism II

Environmental and State-Level Regulatory Factors Affect the Incidence of Autism and Intellectual Disability http://www.ploscompbiol.org Many factors affect the risks for neurodevelopmental maladies such as autism spectrum disorders (ASD) and intellectual disability (ID). To compare environmental, phenotypic, socioeconomic and state-policy factors … Continue reading

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