Category Archives: Genetics

Autism – Shared Epigenetic Changes at or near 12 Months for 68% of ASD

Shared epigenetic changes underlie different types of autism  www.cell.com Individuals with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study published November 17 in Cell. More … Continue reading

Posted in Autism, bowel disease, co-morbid, Environment, Epigenetics, epilepsy, General, Genetics, Gut, IBD, Immune System, Inflammation, Neurology, Schizophrenia, Treatment | Leave a comment

Hygiene Hypothesis and The Gut.

The gut microbiomes of infants have an impact on autoimmunity http://www.aalto.fi/en/current/news/2016-04-28-006/ Exposure to pathogens early in life is beneficial to the education and development of the human immune system. Over the past few decades, the healthcare community has observed an … Continue reading

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2016 CDC Autism Prevalence – 1 in 68

U.S. Autism Rate Unchanged in New CDC Report http://www.jhsph.edu Researchers say it’s too early to tell if rate has stabilized Researchers at the Johns Hopkins Bloomberg School of Public Health contributed to a new U.S. Centers for Disease Control and … Continue reading

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New Shift in Understanding – We are all Autism

Autism genes are in all of us, new research reveals http://www.bristol.ac.uk/news/2016/march/autism-genetics-population.html New light has been shed on the genetic relationship between autistic spectrum disorders (ASD) and ASD-related traits in the wider population, by a team of international researchers including academics … Continue reading

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Glutamate and a range of Disorders

Glutamate transporter dysfunction and major mental illnesses http://www.ncbi.nlm.nih.gov/pubmed/26793898 Abstract Glutamate is the main excitatory neurotransmitter in the central nervous system and plays an important role in most aspects of normal brain function. In this review, we demonstrate that various kinds … Continue reading

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Epilepsy and Autism – Autism and Epilepsy

Bidirectional association between autism spectrum disorder and epilepsy in child and adolescent patients: a population-based cohort study. http://www.ncbi.nlm.nih.gov/pubmed/26791195  Abstract This study aimed to assess whether there is a bidirectional association between autism spectrum disorder (ASD) and epilepsy in child and … Continue reading

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Repeated courses of antibiotics may profoundly alter children’s development II

Repeated courses of antibiotics may profoundly alter children’s development http://www.med.nyu.edu/ A new animal study by NYU Langone Medical Center researchers adds to growing evidence that multiple courses of commonly used antibiotics may have a significant impact on children’s development. In … Continue reading

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Repeated courses of antibiotics may profoundly alter children’s development

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment http://www.nature.com Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic perturbation or nutrient flux. In humans, especially children, microbiota disruption is … Continue reading

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Autism – Environment for Boys , Genetics for Girls

Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins. http://www.ncbi.nlm.nih.gov/pubmed/25973164 BACKGROUND: Autism spectrum disorders (ASDs) are more prevalent in males, suggesting a multiple threshold liability model in which females are, on … Continue reading

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Autism Prevalence – Atlanta 1991 -2010

Trends in the Prevalence of Autism Spectrum Disorder, Cerebral Palsy, Hearing Loss, Intellectual Disability, and Vision Impairment, Metropolitan Atlanta, 1991-2010. http://journals.plos.org/ Free Full Text at Link Abstract This study examined the prevalence and characteristics of autism spectrum disorder (ASD), cerebral … Continue reading

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