Category Archives: epilepsy

Febrile Seizures and Autism – A Marker

Posted on October 21, 2017 by researchinitiative

Febrile Seizures and Epilepsy: Association With Autism and Other Neurodevelopmental Disorders in the Child and Adolescent Twin Study in Sweden. https://www.ncbi.nlm.nih.gov/pubmed/28754226 BACKGROUND: There is a recently well-documented association between childhood epilepsy and earlysymptomaticsyndromeselicitingneurodevelopmentalclinicalexaminations (ESSENCE) including autism spectrum disorder, but the relationship … Continue reading →

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Early Life Immune Activation and ASD

Posted on October 14, 2017 by researchinitiative

Perinatal Immune Activation Produces Persistent Sleep Alterations and Epileptiform Activity in Male Mice. https://www.ncbi.nlm.nih.gov/pubmed/28984294# Abstract Increasing evidence suggests a role for inflammation in neuropsychiatric conditions including autism spectrum disorder (ASD). Previous work in rodents has established that immune activation during … Continue reading →

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Autism – Shared Epigenetic Changes at or near 12 Months for 68% of ASD

Posted on November 20, 2016 by researchinitiative

Shared epigenetic changes underlie different types of autism  www.cell.com Individuals with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study published November 17 in Cell. More … Continue reading →

Posted in Autism, bowel disease, co-morbid, Environment, Epigenetics, epilepsy, General, Genetics, Gut, IBD, Immune System, Inflammation, Neurology, Schizophrenia, Treatment | Leave a comment

Neuropathology of Seizures in Autism

Posted on July 7, 2016 by researchinitiative

Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder. http://www.ncbi.nlm.nih.gov/pubmed/27242398 Abstract This manuscript reviews biological abnormalities shared by autism spectrum disorder (ASD) and epilepsy. Two neuropathological findings are shared by ASD and epilepsy: abnormalities in minicolumn architecture and γ-aminobutyric acid (GABA) … Continue reading →

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Immune System, Epilepsy and the Eye

Posted on July 7, 2016 by researchinitiative

Immune response in the eye following epileptic seizures http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0618-3   Abstract Background Epileptic seizures are associated with an immune response in the brain. However, it is not known whether it can extend to remote areas of the brain, such as … Continue reading →

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Immune Response and Complement system play a Major role in Epilepsy

Posted on March 13, 2016 by researchinitiative

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading →

Posted in Autism, co-morbid, epilepsy, Immune System, Inflammation, Neurology, Treatment, Uncategorized | Leave a comment

Inflammatory Pathways in Epilepsy

Posted on March 13, 2016 by researchinitiative

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/26877106 Abstract BACKGROUND: Accumulating evidence suggests a role for inflammation in the pathophysiology of epilepsy. METHODS: We performed a systematic review and meta-analysis of studies that investigated inflammatory mediators in … Continue reading →

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Autism co-morbidity in Epilepsy – New Spanish Research

Posted on March 13, 2016 by researchinitiative

Prognosis of symptomatic epilepsies in relation to their age of onset, monitored at a neuropediatric section of regional reference over a period of three years]. http://www.ncbi.nlm.nih.gov/pubmed/26961422 AIM: To analyze the factors involved in the prognosis of symptomatic epilepsies in relation … Continue reading →

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A Mother’s Inflammation and Autism

Posted on February 29, 2016 by researchinitiative

How severe maternal inflammation can lead to autism-like behavior http://news.mit.edu/2016/maternal-inflammation-autism-behavior-0128 Immune molecules in infected mothers tied to brain and behavior abnormalities in offspring.   Anne Trafton | MIT News Office January 28, 2016   In 2010, a large study in … Continue reading →

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Gut, IBD, Immune System, Inflammation, influenza, Mice, Neurology, Parents, Toxins, Treatment, Virus | Leave a comment

Epilepsy and Autism – Autism and Epilepsy

Posted on February 28, 2016 by researchinitiative

Bidirectional association between autism spectrum disorder and epilepsy in child and adolescent patients: a population-based cohort study. http://www.ncbi.nlm.nih.gov/pubmed/26791195  Abstract This study aimed to assess whether there is a bidirectional association between autism spectrum disorder (ASD) and epilepsy in child and … Continue reading →

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