Monthly Archives: April 2015

Zinc – The Gut Brain Axis and Autism

Posted on April 23, 2015 by researchinitiative

Zinc in Gut-Brain Interaction in Autism and Neurological Disorders. http://www.ncbi.nlm.nih.gov/pubmed/25878905  Abstract A growing amount of research indicates that abnormalities in the gastrointestinal (GI) system during development might be a common factor in multiple neurological disorders and might be responsible for … Continue reading →

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Autism – Cleanroom Intervention impact on Autism and Immune Dysregulation.

Posted on April 23, 2015 by researchinitiative

A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. http://www.ncbi.nlm.nih.gov/pubmed/25887094 Abstract BACKGROUND: An emerging paradigm suggests children with autism display a unique pattern of environmental, genetic, and epigenetic triggers … Continue reading →

Posted in Asthma, Autism, co-morbid, Environment, Epigenetics, Genetics, Immune System, Neurology, Physiology, Toxins | Tagged , , , , | Leave a comment

Epilepsy and Autism – New Understandings – Single Immune Challenge.

Posted on April 21, 2015 by researchinitiative

Autism-epilepsy connection explored in four studies https://www.aesnet.org/ Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies … Continue reading →

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Autism – Social Deficits driven by expression of Immune Gene Networks

Posted on April 21, 2015 by researchinitiative

Association of brain immune genes with social behavior of inbred mouse strains  http://www.jneuroinflammation.com/content/12/1/75  Background Social deficit is one of the core symptoms of neuropsychiatric diseases, in which immune genes play an important role. Although a few immune genes have been … Continue reading →

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Schizophrenia – The Dual Hit Model

Posted on April 17, 2015 by researchinitiative

Neurodevelopmental Animal Models Reveal the Convergent Role of Neurotransmitter Systems, Inflammation, and Oxidative Stress as Biomarkers of Schizophrenia: Implications for Novel Drug Development. http://www.ncbi.nlm.nih.gov/pubmed/25794269 Abstract Schizophrenia is a life altering disease with a complex etiology and pathophysiology, and although antipsychotics … Continue reading →

Posted in Autism, Bacteria, co-morbid, Environment, Epigenetics, Immune System, Inflammation, influenza, Neurology, Physiology, Schizophrenia, Treatment, Virus | Tagged , , , , , , , | Leave a comment

Genes / Environment – Autism Twin Study

Posted on April 16, 2015 by researchinitiative

The Relationship Among Genetic Heritability, Environmental Effects, and Autism Spectrum Disorders: 37 Pairs of Ascertained Twin Study. Abstract Autism spectrum disorders (ASD) comprise a heterogeneous group of neurodevelopmental disorders that have strong heritability. To better understand the heritable factors in … Continue reading →

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Vitamin D and Autism II

Posted on April 16, 2015 by researchinitiative

Vitamin D status in autism spectrum disorders and the efficacy of vitamin D supplementation in autistic children. http://www.ncbi.nlm.nih.gov/pubmed/25876214 Abstract Objectives Autism spectrum disorder (ASD) is a developmental disorder characterized by pervasive deficits in social interaction, impairment in verbal and non-verbal … Continue reading →

Posted in Autism, co-morbid, Environment, Immune System, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , | 1 Comment

Vitamin D and Autism

Posted on April 16, 2015 by researchinitiative

Autism spectrum disorder and low vitamin D at birth: a sibling control study. http://www.ncbi.nlm.nih.gov/pubmed/25874075 Abstract BACKGROUND: Insufficient vitamin D activity has attracted increasing interest as a possible underlying risk factor in disorders of the central nervous system, including autism. METHODS: … Continue reading →

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Maternal Gestational Diabetes – linked to Autism

Posted on April 14, 2015 by researchinitiative

Intrauterine Exposure to Maternal Gestational Diabetes Associated With Increased Risk of Autism http://jama.jamanetwork.com  Among a group of more than 320,000 children, intrauterine exposure to gestational diabetes mellitus diagnosed by 26 weeks’ gestation was associated with risk of autism spectrum disorders … Continue reading →

Posted in Autism, co-morbid, diabetes, Environment, Epigenetics, Gut, Immune System, Inflammation, Physiology, Treatment | Leave a comment

Chronic Inflammation – Inflammatory Bowel Disease – Hippocampal Neurogenesis

Posted on April 12, 2015 by researchinitiative

Chronic intestinal inflammation alters hippocampal neurogenesis http://www.jneuroinflammation.com/content/12/1/65/abstract Background Adult neurogenesis in the subgranular zone of the hippocampus is involved in learning, memory, and mood control. Decreased hippocampal neurogenesis elicits significant behavioral changes, including cognitive impairment and depression. Inflammatory bowel disease … Continue reading →

Posted in Autism, bowel disease, co-morbid, Depression, Environment, Epigenetics, Genetics, Gut, IBD, Immune System, Inflammation, Toxins, Treatment | Tagged , , , , | Leave a comment