Monthly Archives: April 2015

Zinc – The Gut Brain Axis and Autism

Zinc in Gut-Brain Interaction in Autism and Neurological Disorders.  Abstract A growing amount of research indicates that abnormalities in the gastrointestinal (GI) system during development might be a common factor in multiple neurological disorders and might be responsible for … Continue reading

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Autism – Cleanroom Intervention impact on Autism and Immune Dysregulation.

A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. Abstract BACKGROUND: An emerging paradigm suggests children with autism display a unique pattern of environmental, genetic, and epigenetic triggers … Continue reading

Posted in Asthma, Autism, co-morbid, Environment, Epigenetics, Genetics, Immune System, Neurology, Physiology, Toxins | Tagged , , , , | Leave a comment

Epilepsy and Autism – New Understandings – Single Immune Challenge.

Autism-epilepsy connection explored in four studies Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies … Continue reading

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Autism – Social Deficits driven by expression of Immune Gene Networks

Association of brain immune genes with social behavior of inbred mouse strains  Background Social deficit is one of the core symptoms of neuropsychiatric diseases, in which immune genes play an important role. Although a few immune genes have been … Continue reading

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Schizophrenia – The Dual Hit Model

Neurodevelopmental Animal Models Reveal the Convergent Role of Neurotransmitter Systems, Inflammation, and Oxidative Stress as Biomarkers of Schizophrenia: Implications for Novel Drug Development. Abstract Schizophrenia is a life altering disease with a complex etiology and pathophysiology, and although antipsychotics … Continue reading

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Genes / Environment – Autism Twin Study

The Relationship Among Genetic Heritability, Environmental Effects, and Autism Spectrum Disorders: 37 Pairs of Ascertained Twin Study. Abstract Autism spectrum disorders (ASD) comprise a heterogeneous group of neurodevelopmental disorders that have strong heritability. To better understand the heritable factors in … Continue reading

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Vitamin D and Autism II

Vitamin D status in autism spectrum disorders and the efficacy of vitamin D supplementation in autistic children. Abstract Objectives Autism spectrum disorder (ASD) is a developmental disorder characterized by pervasive deficits in social interaction, impairment in verbal and non-verbal … Continue reading

Posted in Autism, co-morbid, Environment, Immune System, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , | 1 Comment

Vitamin D and Autism

Autism spectrum disorder and low vitamin D at birth: a sibling control study. Abstract BACKGROUND: Insufficient vitamin D activity has attracted increasing interest as a possible underlying risk factor in disorders of the central nervous system, including autism. METHODS: … Continue reading

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Maternal Gestational Diabetes – linked to Autism

Intrauterine Exposure to Maternal Gestational Diabetes Associated With Increased Risk of Autism  Among a group of more than 320,000 children, intrauterine exposure to gestational diabetes mellitus diagnosed by 26 weeks’ gestation was associated with risk of autism spectrum disorders … Continue reading

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Chronic Inflammation – Inflammatory Bowel Disease – Hippocampal Neurogenesis

Chronic intestinal inflammation alters hippocampal neurogenesis Background Adult neurogenesis in the subgranular zone of the hippocampus is involved in learning, memory, and mood control. Decreased hippocampal neurogenesis elicits significant behavioral changes, including cognitive impairment and depression. Inflammatory bowel disease … Continue reading

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