Tag Archives: epilepsy

Febrile Seizures and Autism – A Marker

Febrile Seizures and Epilepsy: Association With Autism and Other Neurodevelopmental Disorders in the Child and Adolescent Twin Study in Sweden. https://www.ncbi.nlm.nih.gov/pubmed/28754226 BACKGROUND: There is a recently well-documented association between childhood epilepsy and earlysymptomaticsyndromeselicitingneurodevelopmentalclinicalexaminations (ESSENCE) including autism spectrum disorder, but the relationship … Continue reading

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Early Life Immune Activation and ASD

Perinatal Immune Activation Produces Persistent Sleep Alterations and Epileptiform Activity in Male Mice. https://www.ncbi.nlm.nih.gov/pubmed/28984294# Abstract Increasing evidence suggests a role for inflammation in neuropsychiatric conditions including autism spectrum disorder (ASD). Previous work in rodents has established that immune activation during … Continue reading

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Autism and Epilepsy – Vagus Nerve Stimulation as Treatment

Autistic spectrum disorder, epilepsy, and vagus nerve stimulation. http://www.ncbi.nlm.nih.gov/pubmed/25922052 Abstract PURPOSE: In individuals with a comorbid autistic spectrum disorder and medically refractory epilepsy, vagus nerve stimulation may offer the potential of seizure control and a positive behavioral side effect profile. … Continue reading

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Epilepsy and Autism – New Understandings – Single Immune Challenge.

Autism-epilepsy connection explored in four studies https://www.aesnet.org/ Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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“Volume Control” in Brain Memory, Learning , Seizures and Autism.

Newly Found ‘Volume Control’ in Brain Promotes Learning, Memory http://www.sciencedaily.com/releases/2013/01/130109124154.htm Jan. 9, 2013 — Scientists have long wondered how nerve cell activity in the brain’s hippocampus, the epicenter for learning and memory, is controlled — too much synaptic communication between … Continue reading

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Glucose Metabolism, Cytotoxic T lymphocytes and mTOR

Cellular Metabolism Arms T Cells to Battle Viruses and Tumors http://www.sciencedaily.com/releases/2012/12/121224113420.htm Dec. 24, 2012 — New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the … Continue reading

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uPAR, Epilepsy and Autism

Urokinase-Type Plasminogen Activator Receptor Modulates Epileptogenesis in Mouse Model of Temporal Lobe Epilepsy. http://www.ncbi.nlm.nih.gov/pubmed/23263886 Department of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland Abstract Mutation in Plaur gene encoding urokinase-type plasminogen activator receptor (uPAR) results … Continue reading

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Top 40 Research Articles of 2012 – Autism

Top 40 Research Articles – ( 40 / 350) The research that asdresearchinitiative believes has contributed greatly to our understanding of ASD and most significantly the care of ASD children. 2012 may be seen by future generations as a breakthrough … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Fragile X, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 3 Comments

CDKL5 – MECP2 and a Mouse

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice. http://www.ncbi.nlm.nih.gov/pubmed/23236174 Departments of Genetics, Neurology, Psychiatry, and Pharmacology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104. Abstract Mutations in the X-linked … Continue reading

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