Monthly Archives: April 2012

Obese Mice and Gut Pathology

Interesting research has been undertaken by French researchers on gut micorflora and obesity. Gut Organisms Could Be Clue in Controlling Obesity Risk http://www.sciencedaily.com/releases/2012/04/120423162223.htm “To determine whether altering one’s bacterial profile can change obesity risk, researchers from the French Institute for … Continue reading

Posted in Autism, co-morbid, Environment, Epigenetics, General, Genetics, Gut, Immune System, Inflammation, Mice, Physiology | Leave a comment

Quick Post – Epilepsy and Autism

Sleep-potentiated epileptic discharges, language regression, and pediatric thalamic lesions http://www.ncbi.nlm.nih.gov/pubmed/22539573 “Ever since Gloor et al.(1) demonstrated that thalamo-cortical interactions were responsible for generalized seizures, alterations of thalamic function have been investigated in the pathophysiology of epilepsy. Today, the thalamus (in … Continue reading

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Quick Post – Pesticides and Autism

University of California researchers,  including Irva Hertz- Picciotto , have called for pesticides to be part of the ongoing environmental investigation of autism risk factors. Tipping the Balance of Autism Risk: Potential Mechanisms Linking Pesticides and Autism. http://www.ncbi.nlm.nih.gov/pubmed/22534084 “Based on … Continue reading

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Quick Post – Pfizer develops new Fragile X drug

Pfizer has developed a new an experimental compound, called GRN-529 for use with Fragile X patients. Some positive results have been shown in social behaviour of mice. Full story here – http://www.news-medical.net/news/20120426/Experimental-drug-for-autism-works-effectively-in-laboratory-mice-Study.aspx Notes – Fragile X “Fragile X Syndrome is … Continue reading

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Quick Post – PD-1 Regulates IgA Selection and Bacterial Composition in the Gut

The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut http://www.sciencemag.org/content/336/6080/485.short Immunoglobulin A (IgA) is essential to maintain the symbiotic balance between gut bacterial communities and the host immune system. Here we provide evidence that the inhibitory … Continue reading

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Quick Post – Microbes in Early Life.

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function http://www.sciencemag.org/content/336/6080/489.short “Exposure to microbes during early childhood is associated with protection from immune-mediated diseases such as inflammatory bowel disease (IBD) and asthma. Here, we show that … Continue reading

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Smoking and Autism ?

Smoking and Autism is there a relationship ? Maternal Smoking During Pregnancy and the Prevalence of Autism Spectrum Disorders Using Data from the Autism and Developmental Disabilities Monitoring Network http://ehp03.niehs.nih.gov/article/info%3Adoi%2F10.1289%2Fehp.1104556 “After accounting for the potential of under-ascertainment bias, we found … Continue reading

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Environment and Autism

1.Lead 2.Methylmercury 3.PCBs 4.Organophosphate pesticides 5.Organochlorine pesticides 6.Endocrine disruptors 7.Automotive exhaust 8.Polycyclic aromatic hydrocarbons 9.Brominated flame retardants 10.Perfluorinated compounds Mount Sinai Children’s Environmental Health Center Publishes a List of the Top Ten Toxic Chemicals Suspected to Cause Autism and Learning … Continue reading

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PCBs – (polychlorinated biphenyls) and Autism

“ScienceDaily (Apr. 25, 2012) — New research from UC Davis and Washington State University shows that PCBs, or polychlorinated biphenyls, launch a cellular chain of events that leads to an overabundance of dendrites — the filament-like projections that conduct electrochemical … Continue reading

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Mental Health of Children in the USA : A Quick Snapshot

Mental Health Disorders among Children – Substance Abuse and Mental Health Services Administration. The full SAMHSA 2010 report is available as PDF download here … http://www.samhsa.gov/newsroom/advisories/1204250726.aspx “One out of eight U.S. children has a mental health disorder. Many U.S. children … Continue reading

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