Monthly Archives: May 2013

Early Brain, Neural Plasticity and Social Language

Early brain responses to words predict developmental outcomes in children with autism http://www.washington.edu/news/2013/05/29/early-brain-responses-to-words-predict-developmental-outcomes-in-children-with-autism/ The pattern of brain responses to words in 2-year-old children with autism spectrum disorder predicted the youngsters’ linguistic, cognitive and adaptive skills at ages 4 and 6, … Continue reading

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Gut and Diabetes

Gut metagenome in European women with normal, impaired and diabetic glucose control http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12198.html Type 2 diabetes (T2D) is a result of complex gene–environment interactions, and several risk factors have been identified, including age, family history, diet, sedentary lifestyle and obesity. … Continue reading

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Immune Mediated Alterations in Brain Development – Lecture New York

Antibodies, Behavior and Cognition: The ABCs of immune-mediated alterations in brain development http://www.eventbrite.com/event/6011856625/# Simons Foundation Lectures Thursday, May 30, 2013 from 4:30 PM to 6:30 PM (EDT) New York, NY About the Speaker                                  Betty Diamond, M.D., is Investigator and … Continue reading

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Prickle2 – WnT pathway – Epilepsy

Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction. http://www.ncbi.nlm.nih.gov/pubmed/23711981 Abstract Autism spectrum disorders (ASDs) have been suggested to arise from abnormalities in the canonical and non-canonical Wnt signaling pathways. However, a … Continue reading

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Gut Bacteria and Brain Function – Probiotics and the food we eat.

Changing Gut Bacteria Through Diet Affects Brain Function http://www.newswise.com/articles/changing-gut-bacteria-through-diet-affects-brain-function-ucla-study-shows Released: 5/28/2013 4:00 PM EDT Source Newsroom: University of California, Los Angeles (UCLA), Health Sciences Newswise — UCLA researchers now have the first evidence that bacteria ingested in food can affect … Continue reading

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Retrospective Research – Lactobacilli, Influenza and the Gut

Oral administration of lactobacilli from human intestinal tract protects mice against influenza virus infection http://onlinelibrary.wiley.com/doi/10.1111/j.1472-765X.2010.02849.x/abstract Abstract Aims:  Our study was conducted to evaluate the potent protective effects of oral administration of probiotic Lactobacillus strains against influenza virus (Flu) infection in … Continue reading

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PTEN in Autism

Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly. http://www.ncbi.nlm.nih.gov/pubmed/23695273 Abstract Unlike some other childhood neurodevelopmental disorders, no diagnostic biochemical marker has been identified in all individuals with an autism spectrum disorder (ASD). This deficit … Continue reading

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Grey Matter – ADHD – Autism

Disorder-specific predictive classification of adolescents with attention deficit hyperactivity disorder (ADHD) relative to autism using structural magnetic resonance imaging. http://www.ncbi.nlm.nih.gov/pubmed/23696841 Abstract OBJECTIVE: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, but diagnosed by subjective clinical and rating measures. The … Continue reading

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Neuregulin-1 : Treatment Implications for Schizophrenia.

Researchers eliminate schizophrenia symptoms in an animal model http://www.eurekalert.org/pub_releases/2013-05/mcog-res052213.php AUGUSTA, Ga. – Overexpression of a gene associated with schizophrenia causes classic symptoms of the disorder that are reversed when gene expression returns to normal, scientists report. They genetically engineered mice … Continue reading

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Commensal Bacteria – Loss of ILC Function and Disease – Implications for Autism ?

Penn Study Shows How Immune System Peacefully Co-exists with “Good” Bacteria http://www.uphs.upenn.edu/news/News_Releases/2013/05/sonnenberg/ Understanding How This Immunological Truce Is Kept Suggests New Ways to Fight Inflammatory Diseases PHILADELPHIA — The human gut is loaded with commensal bacteria – “good” microbes that, … Continue reading

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