Monthly Archives: September 2012

New Research on DSM-V – More confusion

J Autism Dev Disord. 2012 Sep 26. [Epub ahead of print] Brief Report: Comparability of DSM-IV and DSM-5 ASD Research Samples. http://www.ncbi.nlm.nih.gov/pubmed/23011251 Mazefsky CA, McPartland JC, Gastgeb HZ, Minshew NJ. Source Department of Psychiatry, University of Pittsburgh, Webster Hall, Suite … Continue reading

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Optogenetics and Autism – Is this a new treatment paradigm ?

Fascinating article in Discovery magazine surrounding optogenetics … could it be used to develop treatment regimes in autism or aspects of autism ? Controlling Brains With a Flick of a Light Switch http://discovermagazine.com/2012/sep/25-controlling-brains-with-flick-of-light-switch Using the new science of optogenetics, scientists … Continue reading

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SCN1A and Autism – Epilepsy and Behaviours

Mouse with Na(v)1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment. http://www.ncbi.nlm.nih.gov/pubmed/22986304 Laboratory for Neurogenetics, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan; Department of Pediatrics, Graduate School of Medicine, Tokyo Women’s Medical University, … Continue reading

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Autism and Environment II

Two stories from Washington University the first not directly related to autism per se but highlights epigentic changes over generations in mice exposed to dioxin and the second regarding BPA suspected of having some association with autism (http://www.ncbi.nlm.nih.gov/pubmed/22458970). —————————————————————————————— Dioxin … Continue reading

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Environment , toxins , genes and autism.

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions. http://www.ncbi.nlm.nih.gov/pubmed/23010509 Department of Psychiatry and Behavioral Sciences, M.I.N.D. Institute, University of California, Davis, One Shields Avenue, Davis, CA 95618, United States. Electronic address: jschwartzer@ucdavis.edu. Abstract To … Continue reading

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Excess Mortality and Autism – Of Serious Concern.

Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study. http://www.ncbi.nlm.nih.gov/pubmed/23008058 Department of Psychiatry, University of Utah This study’s purpose was to investigate mortality among individuals with autism spectrum disorders … Continue reading

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Gut Bacteria and Type 2 Diabetes – Autism Implications

Gut bacteria could cause diabetes http://news.ku.dk/all_news/2012/2012.9/gut-bacteria-could-cause-diabetes/ GUT BACTERIA AND TYPE 2 DIABETES Studying gut bacteria can reveal a range of human illness. Now, new research shows that the composition of a person’s intestinal bacteria could play an important role in the … Continue reading

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Autism: It’s Not Just in the Head 2007 – 2012 – Retrospective

Autism: It’s Not Just in the Head http://discovermagazine.com/2007/apr/autism-it2019s-not-just-in-the-head/article_view?b_start:int=1&-C The devastating derangements of autism also show up in the gut and in the immune system. That unexpected discovery is sparking new treatments that target the body in addition to the brain. … Continue reading

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Perinatal inflammation and the brain.

[Long-term cerebral effects of perinatal inflammation]. [Article in French] http://www.ncbi.nlm.nih.gov/pubmed/22885003 Inserm U676, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France; Faculté de médecine Denis-Diderot, université Paris-7, 75205 Paris cedex 13, France; PremUP, 75006 Paris, France. Abstract Perinatal inflammation can lead … Continue reading

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Protecting Neonates from inflammation.

Postnatal administration of IL-1Ra exerts neuroprotective effects following perinatal inflammation and/or hypoxic-ischemic injuries. http://www.ncbi.nlm.nih.gov/pubmed/22982341 Girard S, Sébire H, Brochu ME, Briota S, Sarret P, Sébire G. Source Laboratoire de Neurologie Pédiatrique, Département de Pédiatrie, Faculté de Médecine et des Sciences … Continue reading

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