Category Archives: Neurology

Autism – Shared Epigenetic Changes at or near 12 Months for 68% of ASD

Shared epigenetic changes underlie different types of autism  www.cell.com Individuals with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study published November 17 in Cell. More … Continue reading

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Startling Discovery – Immune System Affects and may Control Social Behavior

Shocking New Role Found for the Immune System: Controlling Social Interactions https://news.virginia.edu In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects … Continue reading

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Chronic Lack of Sleep – Linked to Neurological Damage – Implications for Autism ?

 Insomnia Linked to Damage in Brain Communication Networks https://www2.rsna.org At A Glance Twenty-three insomnia patients and 30 healthy controls were examined with diffusion tensor imaging and given questionnaires to evaluate mental status and sleep patterns. Compared to the healthy controls, … Continue reading

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Environment x Genes – Fungicides and Autism

Could a new class of fungicides play a role in autism, neurodegenerative diseases? http://news.unchealthcare.org/news/2016/march/could-a-new-class-of-fungicides-play-a-role-in-autism-neurodegenerative-diseases A new UNC School of Medicine study shows how chemicals designed to protect crops can cause gene expression changes in mouse brain cells that look strikingly … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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Immune Response and Complement system play a Major role in Epilepsy

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading

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Inflammatory Pathways in Epilepsy

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/26877106 Abstract BACKGROUND: Accumulating evidence suggests a role for inflammation in the pathophysiology of epilepsy. METHODS: We performed a systematic review and meta-analysis of studies that investigated inflammatory mediators in … Continue reading

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Autism co-morbidity in Epilepsy – New Spanish Research

Prognosis of symptomatic epilepsies in relation to their age of onset, monitored at a neuropediatric section of regional reference over a period of three years]. http://www.ncbi.nlm.nih.gov/pubmed/26961422 AIM: To analyze the factors involved in the prognosis of symptomatic epilepsies in relation … Continue reading

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Breakthrough – Autism, Immune Cells and Pruning

The Brain’s Gardeners: Immune Cells ‘Prune’ Connections Between Neurons https://www.urmc.rochester.edu A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring … Continue reading

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