Category Archives: Neurology

Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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Immune Response and Complement system play a Major role in Epilepsy

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading

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Inflammatory Pathways in Epilepsy

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/26877106 Abstract BACKGROUND: Accumulating evidence suggests a role for inflammation in the pathophysiology of epilepsy. METHODS: We performed a systematic review and meta-analysis of studies that investigated inflammatory mediators in … Continue reading

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Autism co-morbidity in Epilepsy – New Spanish Research

Prognosis of symptomatic epilepsies in relation to their age of onset, monitored at a neuropediatric section of regional reference over a period of three years]. http://www.ncbi.nlm.nih.gov/pubmed/26961422 AIM: To analyze the factors involved in the prognosis of symptomatic epilepsies in relation … Continue reading

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Breakthrough – Autism, Immune Cells and Pruning

The Brain’s Gardeners: Immune Cells ‘Prune’ Connections Between Neurons https://www.urmc.rochester.edu A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring … Continue reading

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A Mother’s Inflammation and Autism

How severe maternal inflammation can lead to autism-like behavior http://news.mit.edu/2016/maternal-inflammation-autism-behavior-0128 Immune molecules in infected mothers tied to brain and behavior abnormalities in offspring.   Anne Trafton | MIT News Office January 28, 2016   In 2010, a large study in … Continue reading

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Gut, IBD, Immune System, Inflammation, influenza, Mice, Neurology, Parents, Toxins, Treatment, Virus | Leave a comment

Gastrointestinal Disorer, Autism and Behavioural Problems

Gastrointestinal symptoms and behavioral problems in preschoolers with Autism Spectrum Disorder.  http://www.ncbi.nlm.nih.gov/pubmed/26748423 Abstract Gastrointestinal (GI) symptoms are frequently reported in children with Autism Spectrum Disorder (ASD), and an impact of GI comorbidity on ASD behavioral problems has been hypothesized. A … Continue reading

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Glutamate and a range of Disorders

Glutamate transporter dysfunction and major mental illnesses http://www.ncbi.nlm.nih.gov/pubmed/26793898 Abstract Glutamate is the main excitatory neurotransmitter in the central nervous system and plays an important role in most aspects of normal brain function. In this review, we demonstrate that various kinds … Continue reading

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Epilepsy and Autism – Autism and Epilepsy

Bidirectional association between autism spectrum disorder and epilepsy in child and adolescent patients: a population-based cohort study. http://www.ncbi.nlm.nih.gov/pubmed/26791195  Abstract This study aimed to assess whether there is a bidirectional association between autism spectrum disorder (ASD) and epilepsy in child and … Continue reading

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White Matter and Autism

Atypical age-dependent effects of autism on white matter microstructure in children of 2-7 years. http://www.ncbi.nlm.nih.gov/pubmed/26663516 Abstract Atypical age-dependent changes of white matter (WM) microstructure play a central role in abnormal brain maturation of the children with autism spectrum disorder (ASD), … Continue reading

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