Tag Archives: signaling pathways

Autism Gut Link – New and Profound Research

Gut Instincts: Researchers Discover First Clues on How Gut Health Influences Brain Health https://news.weill.cornell.edu/news/2019/10/gut-instincts-researchers-discover-first-clues-on-how-gut-health-influences-brain New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine … Continue reading

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Postnatal Immune System Activation and Autism

McLean Hospital Neuroscientists Find Immune System in Newborns May Affect Developing Brain http://www.mcleanhospital.org/news/2018/01/12/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing Belmont, MA – McLean Hospital neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep … Continue reading

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Risperidone and Inflammation : Positive implications for Autism

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/22176740 Department of Pharmacology, Faculty of Medicine, Complutense University, Madrid, Spain. Abstract Inflammation, caused by both external and endogenous factors, has been implicated as a main … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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Maternal Inflammation – Significant Role in Autism II

Prenatal inflammation linked to autism risk http://www.niehs.nih.gov/news/newsroom/releases/2013/january24/index.cfm Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the … Continue reading

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Maternal Inflammation – Significant Role in Autism

Elevated maternal C-reactive protein and autism in a national birth cohort. http://www.ncbi.nlm.nih.gov/pubmed/23337946 1] Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY, USA [2] Department of Epidemiology, Columbia University Mailman School … Continue reading

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Toxins , Genetic Susceptibility and Autism

Toxicity of the Flame-retardant BDE-49 on Brain Mitochondria and Neurons Enhanced by a PTEN-deficient Background. http://www.ncbi.nlm.nih.gov/pubmed/23288049 Department of Molecular Biosciences, School of Veterinary Medicine. Abstract Polybrominated diphenyl ethers (PBDEs) represent an important group of flame-retardants extensively used, which tonnage in … Continue reading

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Risk Gene for Alzheimer’s at Birth – Autism Implications.

Risk Genes for Alzheimer’s and Mental Illness Linked to Brain Changes at Birth http://www.sciencedaily.com/releases/2013/01/130102205459.htm Jan. 2, 2013 — Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer’s disease, schizophrenia, and autism … Continue reading

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Converging Enivronment and Genetics – Key Signalling Pathways

Neuronal connectivity as a convergent target of gene-environment interactions that confer risk for Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/23269408 Department of Molecular Biosciences, University of California at Davis School of Veterinary Medicine Abstract Evidence implicates environmental factors in the pathogenesis of Autism … Continue reading

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Glucose Metabolism, Cytotoxic T lymphocytes and mTOR

Cellular Metabolism Arms T Cells to Battle Viruses and Tumors http://www.sciencedaily.com/releases/2012/12/121224113420.htm Dec. 24, 2012 — New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the … Continue reading

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