Monthly Archives: August 2012

Asperger’s – Autism : Mood Disorders and Risk

Mood disorders in mothers of children on the autism spectrum are associated with higher functioning autism. http://www.ncbi.nlm.nih.gov/pubmed/22934172 Department of Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 3901 Greenspring Avenue, Baltimore, MD 21211, USA. Abstract Mood disorders occur … Continue reading

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It’s the Immune System Stupid ?

Paul Patterson  http://infectiousbehavior.wordpress.com/casts a critical eye over a NY Times opinion piece by Moises Velasquez-Manoff author of “An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases.” An Immune Disorder at the Root of Autism http://www.nytimes.com/2012/08/26/opinion/sunday/immune-disorders-and-autism.html?pagewanted=all Here’s … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , | 1 Comment

Cytokines, ASD and the Neonatal period.

Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. http://www.ncbi.nlm.nih.gov/pubmed/22917523 The aim of the study was to analyze cytokine profiles in neonatal dried blood samples (n-DBSS) … Continue reading

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Cytokines , ASD and the Environment

Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment. http://www.ncbi.nlm.nih.gov/pubmed/22918031 Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming number of individuals. The etiological basis of ASD is unclear, and evidence suggests it involves both … Continue reading

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The Problem with Dad – Genetic Research Harvard

Most Mutations Come from Dad http://hms.harvard.edu/content/most-mutations-come-dad Humans inherit more than three times as many mutations from their fathers as from their mothers, and mutation rates increase with the father’s age but not the mother’s, researchers have found in the largest … Continue reading

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Human Evolution and the Gene – Implications for Autism

More sophisticated wiring, not just a bigger brain, helped humans evolve beyond chimps http://www.uclahealth.org/body.cfm?id=561&action=detail&ref=1987 Human and chimp brains look anatomically similar because both evolved from the same ancestor millions of years ago. But where does the chimp brain end and … Continue reading

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Stress can effect Multiple Generations

Male Mice Exposed to Chronic Social Stress Have Anxious Female Offspring http://now.tufts.edu/news-releases/male-mice-exposed-chronic-social-stress-have- Tufts University Press Release BOSTON — A study in mice conducted by researchers at Tufts University School of Medicine suggests that a woman’s risk of anxiety and dysfunctional … Continue reading

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Autism in Sweden – Data from Stockholm Youth Cohort

Autism spectrum disorders in the stockholm youth cohort: design, prevalence and validity. http://www.ncbi.nlm.nih.gov/pubmed/22911770 Idring S, Rai D, Dal H, Dalman C, Sturm H, Zander E, Lee BK, Serlachius E, Magnusson C. Source Division of Public Health Epidemiology, Department of Public … Continue reading

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Maternal antibodies and Autism – Review

Maternal and fetal anti-brain antibodies in development and disease. http://www.ncbi.nlm.nih.gov/pubmed/22911883 Recent evidence has emerged indicating that the maternal immune response can have a substantial deleterious impact on prenatal development (Croen et al., 2008). The maternal immune response is largely sequestered … Continue reading

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Microbiology: Inflamed guts boost bad bacteria

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota. http://www.ncbi.nlm.nih.gov/pubmed/22903521 Abstract Inflammation alters host physiology to promote cancer, as seen in colitis-associated colorectal cancer (CRC). Here, we identify the intestinal microbiota as a target of inflammation that impacts the progression of … Continue reading

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