Monthly Archives: March 2016

Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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New Shift in Understanding – We are all Autism

Autism genes are in all of us, new research reveals http://www.bristol.ac.uk/news/2016/march/autism-genetics-population.html New light has been shed on the genetic relationship between autistic spectrum disorders (ASD) and ASD-related traits in the wider population, by a team of international researchers including academics … Continue reading

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Immune Response and Complement system play a Major role in Epilepsy

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading

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Inflammatory Pathways in Epilepsy

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/26877106 Abstract BACKGROUND: Accumulating evidence suggests a role for inflammation in the pathophysiology of epilepsy. METHODS: We performed a systematic review and meta-analysis of studies that investigated inflammatory mediators in … Continue reading

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Autism co-morbidity in Epilepsy – New Spanish Research

Prognosis of symptomatic epilepsies in relation to their age of onset, monitored at a neuropediatric section of regional reference over a period of three years]. http://www.ncbi.nlm.nih.gov/pubmed/26961422 AIM: To analyze the factors involved in the prognosis of symptomatic epilepsies in relation … Continue reading

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Breakthrough – Autism, Immune Cells and Pruning

The Brain’s Gardeners: Immune Cells ‘Prune’ Connections Between Neurons https://www.urmc.rochester.edu A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring … Continue reading

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Maternal Care – Key to Autism

Obesity, Diabetes in Mom Increases Risk of Autism in Child http://www.jhsph.edu/news/news-releases/2016/obesity-diabetes-in-mom-increases-risk-of-autism-in-child.html New study offers new evidence that autism spectrum disorder risks may begin in utero Children born to obese women with diabetes are more than four times as likely to … Continue reading

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