Monthly Archives: February 2015

Genetic Overlap – Fever Associated Epilepsy and Autism.

Posted on February 28, 2015 by researchinitiative

Investigating the genetic basis of fever-associated syndromic epilepsies using copy number variation analysis. http://www.ncbi.nlm.nih.gov/pubmed/25690317 Abstract Fever-associated syndromic epilepsies ranging from febrile seizures plus (FS+) to Dravet syndrome have a significant genetic component. However, apart from SCN1A mutations in >80% of … Continue reading →

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Peanut Allergy – Autism and HLA

Posted on February 28, 2015 by researchinitiative

Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. http://www.ncbi.nlm.nih.gov/pubmed/25710614 Abstract Food allergy (FA) affects 2%-10% of US children and is a growing clinical and public health problem. Here we conduct the first genome-wide … Continue reading →

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Prenatal Stress and the Development of Socioemotional Behavior

Posted on February 28, 2015 by researchinitiative

Prenatal stress alters the development of socioemotional behavior and amygdala neuron excitability in rats. http://www.ncbi.nlm.nih.gov/pubmed/25716930 Abstract Prenatal stress (PS) is a risk factor for neurodevelopmental disorders with diverse ages of onset and socioemotional symptoms. Some PS-linked disorders involve characteristic social … Continue reading →

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Nature Special – Innovations in the Microbiome

Posted on February 28, 2015 by researchinitiative

Innovations in the Microbiome ========================= **The Microbes Within David Grogan http://links.ealert.nature.com/ctt?kn=98&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Gut Microbiome: The Peacekeepers Moises Velasquez-Manoff http://links.ealert.nature.com/ctt?kn=81&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Why Microbiome Treatments Could Pay Off Soon Rob Knight http://links.ealert.nature.com/ctt?kn=90&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **The Gene–Microbe Link Ruth E. Ley http://links.ealert.nature.com/ctt?kn=88&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Your Microbes at Work: Fiber … Continue reading →

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, General, Genetics, Gut, IBD, Immune System, Inflammation, influenza, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Toxins, Treatment, Virus | Leave a comment

New Thinking – Antibiotics and Harmful Bacteria

Posted on February 24, 2015 by researchinitiative

Antibiotics give rise to new communities of harmful bacteria http://uncnews.unc.edu Researchers identify unexpected activity of antibiotics, potentially reshaping our understanding of why antibiotics evolved and pointing to broad health implications (Chapel Hill, N.C. – Feb. 23, 2015) – Most people … Continue reading →

Posted in Autism, Bacteria, bowel disease, Environment, Toxins | Leave a comment

Natural Rhythms and the Development of Mental Illness

Posted on February 24, 2015 by researchinitiative

Deconstructing mental illness through ultradian rhythms http://www.douglas.qc.ca/news/1326 Might living a structured life with regularly established meal times and early bedtimes lead to a better life and perhaps even prevent the onset of mental illness? That’s what’s suggested in a study … Continue reading →

Posted in Autism, co-morbid, Schizophrenia, Treatment | Leave a comment

Allergy, Autoimmune Diseases and Autism – Kaiser Permanente Study

Posted on February 17, 2015 by researchinitiative

Immune Mediated Conditions in Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/25681541 Abstract We conducted a case-control study among members of Kaiser Permanente Northern California (KPNC) born between 1980 and 2003 to determine the prevalence of immune-mediated conditions in individuals with autism, investigate whether … Continue reading →

Posted in Allergy, Asthma, Autism, co-morbid, Gut, IBD, Immune System, Inflammation, Treatment | Leave a comment

Maternal Immune Activation and Hyperactive Immune Response

Posted on February 8, 2015 by researchinitiative

Maternal Lipopolysaccharide Exposure Promotes Immunological Functional Changes in Adult Offspring CD4+ T Cells. http://www.ncbi.nlm.nih.gov/pubmed/25640465 Abstract PROBLEM: Maternal immune activation (MIA) is a risk factor for autism and schizophrenia. However, how MIA affects offspring immune function remains unknown. METHOD OF STUDY: … Continue reading →

Posted in Autism, Immune System, Inflammation, influenza, Mice, Neurology, Physiology, Treatment, Virus | Leave a comment

Early Life Seizures and Autism – Retrospective

Posted on February 8, 2015 by researchinitiative

Early-life seizures result in deficits in social behavior and learning. http://www.ncbi.nlm.nih.gov/pubmed/24685665 Abstract Children with epilepsy show a high co-morbidity with psychiatric disorders and autism. One of the critical determinants of a child’s behavioral outcome with autism and cognitive dysfunction is … Continue reading →

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Single Early Life Seizure and Autism Outcome

Posted on February 8, 2015 by researchinitiative

Behavioral changes following a single episode of early-life seizures support the latent development of an autistic phenotype. http://www.ncbi.nlm.nih.gov/pubmed/25659043 Abstract We probed the developmental and behavioral consequences of a single episode of kainic acid-induced early-life seizures (KA-ELS) in the rat on … Continue reading →

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