Category Archives: Epigenetics

Autism – Shared Epigenetic Changes at or near 12 Months for 68% of ASD

Shared epigenetic changes underlie different types of autism  www.cell.com Individuals with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study published November 17 in Cell. More … Continue reading

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Hygiene Hypothesis and The Gut.

The gut microbiomes of infants have an impact on autoimmunity http://www.aalto.fi/en/current/news/2016-04-28-006/ Exposure to pathogens early in life is beneficial to the education and development of the human immune system. Over the past few decades, the healthcare community has observed an … Continue reading

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A Mother’s Inflammation and Autism

How severe maternal inflammation can lead to autism-like behavior http://news.mit.edu/2016/maternal-inflammation-autism-behavior-0128 Immune molecules in infected mothers tied to brain and behavior abnormalities in offspring.   Anne Trafton | MIT News Office January 28, 2016   In 2010, a large study in … Continue reading

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Glutamate and a range of Disorders

Glutamate transporter dysfunction and major mental illnesses http://www.ncbi.nlm.nih.gov/pubmed/26793898 Abstract Glutamate is the main excitatory neurotransmitter in the central nervous system and plays an important role in most aspects of normal brain function. In this review, we demonstrate that various kinds … Continue reading

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Inflammatory Bowel Disease and Autism – Significant Increased Prevalence

Prevalence of Inflammatory Bowel Disease Among Patients with Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/26218138 The objective of this study was to measure the prevalence of inflammatory bowel disease (IBD) among patients with autism spectrum disorders (ASD), which has not been well described … Continue reading

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Bacterial Infection , Zinc Treatment and Autism

Lipopolysaccharide Exposure Induces Maternal Hypozincemia, and Prenatal Zinc Treatment Prevents Autistic-Like Behaviors and Disturbances in the Striatal Dopaminergic and mTOR Systems of Offspring. http://www.ncbi.nlm.nih.gov/pubmed/26218250 Abstract Autism is characterized by social deficits, repetitive behaviors, and cognitive inflexibility. The risk factors appear … Continue reading

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Autism and Industrial Pollution

Autism spectrum disorder prevalence and proximity to industrial facilities releasing arsenic, lead or mercury. http://www.ncbi.nlm.nih.gov/pubmed/26218563 Abstract Prenatal and perinatal exposures to air pollutants have been shown to adversely affect birth outcomes in offspring and may contribute to prevalence of autism … Continue reading

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Eczema and Autism – The Association

Association Between Atopic Dermatitis and Autism Spectrum Disorders: A Systematic Review. http://www.ncbi.nlm.nih.gov/pubmed/26254000 Atopic dermatitis (AD) is an allergic disorder caused by both immunological dysregulation and epidermal barrier defect. Several studies have investigated the association between AD and mental health disorders. … Continue reading

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Zinc – The Gut Brain Axis and Autism

Zinc in Gut-Brain Interaction in Autism and Neurological Disorders. http://www.ncbi.nlm.nih.gov/pubmed/25878905  Abstract A growing amount of research indicates that abnormalities in the gastrointestinal (GI) system during development might be a common factor in multiple neurological disorders and might be responsible for … Continue reading

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Autism – Cleanroom Intervention impact on Autism and Immune Dysregulation.

A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. http://www.ncbi.nlm.nih.gov/pubmed/25887094 Abstract BACKGROUND: An emerging paradigm suggests children with autism display a unique pattern of environmental, genetic, and epigenetic triggers … Continue reading

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