Category Archives: Mice

The Gut, Microbes and Rheumatoid Arthritis

Study: Gut Bacteria can Cause, Predict and Prevent Rheumatoid Arthritis http://newsnetwork.mayoclinic.org ROCHESTER, Minn. — The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at … Continue reading

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A Mother’s Inflammation and Autism

How severe maternal inflammation can lead to autism-like behavior http://news.mit.edu/2016/maternal-inflammation-autism-behavior-0128 Immune molecules in infected mothers tied to brain and behavior abnormalities in offspring.   Anne Trafton | MIT News Office January 28, 2016   In 2010, a large study in … Continue reading

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Air Pollution and Autism – Neurotoxicity of Traffic

Neurotoxicity of traffic-related air pollution. http://www.ncbi.nlm.nih.gov/pubmed/26610921 Abstract The central nervous system is emerging as an important target for adverse health effects of air pollution, where it may contribute to neurodevelopmental and neurodegenerative disorders. Air pollution comprises several components, including particulate … Continue reading

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Repeated courses of antibiotics may profoundly alter children’s development

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment http://www.nature.com Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic perturbation or nutrient flux. In humans, especially children, microbiota disruption is … Continue reading

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Nature Special – Innovations in the Microbiome

Innovations in the Microbiome ========================= **The Microbes Within David Grogan http://links.ealert.nature.com/ctt?kn=98&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Gut Microbiome: The Peacekeepers Moises Velasquez-Manoff http://links.ealert.nature.com/ctt?kn=81&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Why Microbiome Treatments Could Pay Off Soon Rob Knight http://links.ealert.nature.com/ctt?kn=90&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **The Gene–Microbe Link Ruth E. Ley http://links.ealert.nature.com/ctt?kn=88&ms=NDgxMDM3OTcS1&r=MjA1NzQ2MzIyOAS2&b=2&j=NjIzMTMwNzQxS0&mt=1&rt=0 **Your Microbes at Work: Fiber … Continue reading

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, General, Genetics, Gut, IBD, Immune System, Inflammation, influenza, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Toxins, Treatment, Virus | Leave a comment

Maternal Immune Activation and Hyperactive Immune Response

Maternal Lipopolysaccharide Exposure Promotes Immunological Functional Changes in Adult Offspring CD4+ T Cells. http://www.ncbi.nlm.nih.gov/pubmed/25640465 Abstract PROBLEM: Maternal immune activation (MIA) is a risk factor for autism and schizophrenia. However, how MIA affects offspring immune function remains unknown. METHOD OF STUDY: … Continue reading

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Early Life Seizures and Autism – Retrospective

Early-life seizures result in deficits in social behavior and learning. http://www.ncbi.nlm.nih.gov/pubmed/24685665 Abstract Children with epilepsy show a high co-morbidity with psychiatric disorders and autism. One of the critical determinants of a child’s behavioral outcome with autism and cognitive dysfunction is … Continue reading

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Drug Reverses Autism in Fragile X Mouse Model

Century-Old Drug Reverses Autism-like Symptoms in Fragile X Mouse Model http://ucsdnews.ucsd.edu Autism spectrum disorders (ASD) affect 1 to 2 percent of children in the United States. Hundreds of genetic and environmental factors have been shown to increase the risk of … Continue reading

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Blood Brain Barrier Permeability – Gut Microbiome

Gut microbiota influences blood-brain barrier permeability http://ki.se/en A new study in mice, conducted by researchers at Sweden’s Karolinska Institutet together with colleagues in Singapore and the United States, shows that our natural gut-residing microbes can influence the integrity of the … Continue reading

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The Microbiome – Brain Connection

Could gut microbes help us treat brain disorders? Mounting research tightens their connection with the brain  http://www.kavlifoundation.org January 8, 2015 The trillions of microbes that inhabit the human body, collectively called the microbiome, are estimated to weigh two to six … Continue reading

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