Tag Archives: mice

Postnatal Immune System Activation and Autism

McLean Hospital Neuroscientists Find Immune System in Newborns May Affect Developing Brain http://www.mcleanhospital.org/news/2018/01/12/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing Belmont, MA – McLean Hospital neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep … Continue reading

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New Treatment for Rheumatoid Arthritis

New strategy prevents rheumatoid arthritis in mice http://www.dana-farber.org/Newsroom/News-Releases/New-strategy-prevents-rheumatoid-arthritis-in-mice.aspx Infusions of regulatory T cells turn off autoimmune attack on joints Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis … Continue reading

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The Gut and Malnutrition

Gut microbes at root of severe malnutrition in kids https://news.wustl.edu/news/Pages/24874.aspx A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition. The … Continue reading

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Maternal Infection, Autism and central dopamine (DA) system.

Effect of maternal lipopolysaccharide administration on the development of dopaminergic receptors and transporter in the rat offspring. http://www.ncbi.nlm.nih.gov/pubmed/23349891 Departments of Psychiatry and Neurology and Neurosurgery, McGill University, and Douglas Mental Health University Institute, Montreal, Quebec, Canada. Abstract Epidemiological evidence supports … Continue reading

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GI Bacteria, Autoimmune Disease and Hormones.

GI Tract Bacteria May Protect Against Autoimmune Disease http://www.sciencedaily.com/releases/2013/01/130117133003.htm Jan. 17, 2013 — Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 … Continue reading

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Maternal Infection, a Mouse and Autism.

Aberrant Cerebellar Neurotrophin-3 Expression Induced by Lipopolysaccharide Exposure During Brain Development. http://www.ncbi.nlm.nih.gov/pubmed/23319369 Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. Abstract Autism is a developmental disorder affecting communication, social interaction, motor skills, … Continue reading

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An Enriching Environment : Positive Effects on Autism ?

The effects of enriched environment on BDNF expression in the mouse cerebellum depending on the length of exposure. http://www.ncbi.nlm.nih.gov/pubmed/23295397 Área de Psicobiología, Universidad Jaume I, Castellon de la Plana, España. Abstract Environmental enrichment (EE) has been proposed as a factor … Continue reading

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Interesting Results from Organophospahtes and Autism in Mice

Decreased Reelin Expression and Organophosphate Pesticide Exposure Alters Mouse Behavior and Brain Morphology. http://www.ncbi.nlm.nih.gov/pubmed/23298182 Genetic and environmental factors are both likely to contribute to neurodevelopmental disorders, including autism spectrum disorders. In this study, we examined the combinatorial effect of two … Continue reading

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New Ideas with Worms.

Parasitic worms may help treat diseases associated with obesity http://news.uga.edu/releases/article/parasitic-worms-may-help-treat-diseases-associated-with-obesity/ Athens, Ga. – On the list of undesirable medical conditions, a parasitic worm infection surely ranks fairly high. Although modern pharmaceuticals have made them less of a threat in some … Continue reading

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Valproic Acid and Schizophrenia in Mice

Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice. http://www.ncbi.nlm.nih.gov/pubmed/23272119 Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada. Abstract BACKGROUND: Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility … Continue reading

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