Tag Archives: immune system

Postnatal Immune System Activation and Autism

McLean Hospital Neuroscientists Find Immune System in Newborns May Affect Developing Brain http://www.mcleanhospital.org/news/2018/01/12/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing Belmont, MA – McLean Hospital neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep … Continue reading

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Febrile Seizures and Autism – A Marker

Febrile Seizures and Epilepsy: Association With Autism and Other Neurodevelopmental Disorders in the Child and Adolescent Twin Study in Sweden. https://www.ncbi.nlm.nih.gov/pubmed/28754226 BACKGROUND: There is a recently well-documented association between childhood epilepsy and earlysymptomaticsyndromeselicitingneurodevelopmentalclinicalexaminations (ESSENCE)┬áincluding autism spectrum disorder, but the relationship … Continue reading

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Early Life Immune Activation and ASD

Perinatal Immune Activation Produces Persistent Sleep Alterations and Epileptiform Activity in Male Mice. https://www.ncbi.nlm.nih.gov/pubmed/28984294# Abstract Increasing evidence suggests a role for inflammation in neuropsychiatric conditions including autism spectrum disorder (ASD). Previous work in rodents has established that immune activation during … Continue reading

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Maternal Immune System linked to Autism outcome

Mum’s immune response could trigger social deficits for kids with autism https://sydney.edu.au/news-opinion/news/2017/10/10/mum-s-immune-response-could-trigger-social-deficits-for-kids-wit.html Unlocking autism with applied research Children with autism are more likely to show severe social symptoms if their mother had chronic asthma or allergies while pregnant, the University … Continue reading

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Autism – Cleanroom Intervention impact on Autism and Immune Dysregulation.

A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. http://www.ncbi.nlm.nih.gov/pubmed/25887094 Abstract BACKGROUND: An emerging paradigm suggests children with autism display a unique pattern of environmental, genetic, and epigenetic triggers … Continue reading

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Epilepsy and Autism – New Understandings – Single Immune Challenge.

Autism-epilepsy connection explored in four studies https://www.aesnet.org/ Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies … Continue reading

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Top Autism Papers – 2013

1. Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders http://www.cell.com/abstract/S0092-8674%2813%2901473-6 Full Paper at Link Highlights The MIA model recapitulates GI comorbidities linked to a subset of ASD individuals Targeting the microbiota treats specific GI and behavioral symptoms Gut … Continue reading

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New Treatment for Rheumatoid Arthritis

New strategy prevents rheumatoid arthritis in mice http://www.dana-farber.org/Newsroom/News-Releases/New-strategy-prevents-rheumatoid-arthritis-in-mice.aspx Infusions of regulatory T cells turn off autoimmune attack on joints Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis … Continue reading

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The Gut and Malnutrition

Gut microbes at root of severe malnutrition in kids https://news.wustl.edu/news/Pages/24874.aspx A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition. The … Continue reading

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Risperidone and Inflammation : Positive implications for Autism

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/22176740 Department of Pharmacology, Faculty of Medicine, Complutense University, Madrid, Spain. Abstract Inflammation, caused by both external and endogenous factors, has been implicated as a main … Continue reading

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