Tag Archives: virus

Postnatal Immune System Activation and Autism

McLean Hospital Neuroscientists Find Immune System in Newborns May Affect Developing Brain http://www.mcleanhospital.org/news/2018/01/12/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing Belmont, MA – McLean Hospital neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep … Continue reading

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Febrile Seizures and Autism – A Marker

Febrile Seizures and Epilepsy: Association With Autism and Other Neurodevelopmental Disorders in the Child and Adolescent Twin Study in Sweden. https://www.ncbi.nlm.nih.gov/pubmed/28754226 BACKGROUND: There is a recently well-documented association between childhood epilepsy and earlysymptomaticsyndromeselicitingneurodevelopmentalclinicalexaminations (ESSENCE) including autism spectrum disorder, but the relationship … Continue reading

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Early Life Immune Activation and ASD

Perinatal Immune Activation Produces Persistent Sleep Alterations and Epileptiform Activity in Male Mice. https://www.ncbi.nlm.nih.gov/pubmed/28984294# Abstract Increasing evidence suggests a role for inflammation in neuropsychiatric conditions including autism spectrum disorder (ASD). Previous work in rodents has established that immune activation during … Continue reading

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Epilepsy and Autism – New Understandings – Single Immune Challenge.

Autism-epilepsy connection explored in four studies https://www.aesnet.org/ Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies … Continue reading

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Schizophrenia – The Dual Hit Model

Neurodevelopmental Animal Models Reveal the Convergent Role of Neurotransmitter Systems, Inflammation, and Oxidative Stress as Biomarkers of Schizophrenia: Implications for Novel Drug Development. http://www.ncbi.nlm.nih.gov/pubmed/25794269 Abstract Schizophrenia is a life altering disease with a complex etiology and pathophysiology, and although antipsychotics … Continue reading

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Risperidone and Inflammation : Positive implications for Autism

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/22176740 Department of Pharmacology, Faculty of Medicine, Complutense University, Madrid, Spain. Abstract Inflammation, caused by both external and endogenous factors, has been implicated as a main … Continue reading

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Nerve Growth Factor and Non Verbal Communication.

QTL replication and targeted association highlight the nerve growth factor gene for nonverbal communication deficits in autism spectrum disorders. http://www.ncbi.nlm.nih.gov/pubmed/22105621 Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Abstract Autism Spectrum Disorder (ASD) … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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Maternal Inflammation – Significant Role in Autism II

Prenatal inflammation linked to autism risk http://www.niehs.nih.gov/news/newsroom/releases/2013/january24/index.cfm Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the … Continue reading

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Maternal Inflammation – Significant Role in Autism

Elevated maternal C-reactive protein and autism in a national birth cohort. http://www.ncbi.nlm.nih.gov/pubmed/23337946 1] Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY, USA [2] Department of Epidemiology, Columbia University Mailman School … Continue reading

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