Tag Archives: genes

Autism – Social Deficits driven by expression of Immune Gene Networks

Posted on April 21, 2015 by researchinitiative

Association of brain immune genes with social behavior of inbred mouse strains  http://www.jneuroinflammation.com/content/12/1/75  Background Social deficit is one of the core symptoms of neuropsychiatric diseases, in which immune genes play an important role. Although a few immune genes have been … Continue reading →

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Genes / Environment – Autism Twin Study

Posted on April 16, 2015 by researchinitiative

The Relationship Among Genetic Heritability, Environmental Effects, and Autism Spectrum Disorders: 37 Pairs of Ascertained Twin Study. Abstract Autism spectrum disorders (ASD) comprise a heterogeneous group of neurodevelopmental disorders that have strong heritability. To better understand the heritable factors in … Continue reading →

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Risperidone and Inflammation : Positive implications for Autism

Posted on January 31, 2013 by researchinitiative

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/22176740 Department of Pharmacology, Faculty of Medicine, Complutense University, Madrid, Spain. Abstract Inflammation, caused by both external and endogenous factors, has been implicated as a main … Continue reading →

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Inflammatory Cytokines and Autism : A Relationship

Posted on January 30, 2013 by researchinitiative

Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: a preliminary report. http://www.ncbi.nlm.nih.gov/pubmed/23353117 Department of Psychiatry and Behavioral Sciences, Emory University, USA. Abstract 22q11.2 deletion syndrome (22q11DS) is a genetic disorder that conveys a significant risk … Continue reading →

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mtDNA and Autism

Posted on January 28, 2013 by researchinitiative

Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism. http://www.ncbi.nlm.nih.gov/pubmed/23347615 ABSTRACT: BACKGROUND: The mitochondrial genome (mtDNA) is particularly susceptible to damage mediated by reactive oxygen species (ROS). Although elevated ROS production and elevated biomarkers of … Continue reading →

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Zinc Homeostasis and Autism

Posted on January 28, 2013 by researchinitiative

Environmental factors in autism. http://www.ncbi.nlm.nih.gov/pubmed/23346059 WG Molecular Analysis of Synaptopathies, Neurology Department, Neurocenter of Ulm University Ulm, Germany. Abstract Autism is a neurodevelopmental disorders characterized by impairments in communication and social behavior, and by repetitive behaviors. Although genetic factors might … Continue reading →

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GI Bacteria, Autoimmune Disease and Hormones.

Posted on January 18, 2013 by researchinitiative

GI Tract Bacteria May Protect Against Autoimmune Disease http://www.sciencedaily.com/releases/2013/01/130117133003.htm Jan. 17, 2013 — Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 … Continue reading →

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Paternal Age : No Influence on CNV

Posted on January 17, 2013 by researchinitiative

Increased paternal age and the influence on burden of genomic copy number variation in the general population. http://www.ncbi.nlm.nih.gov/pubmed/23315237 Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht The Netherlands Abstract Genomic copy number variations (CNVs) and increased … Continue reading →

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Interesting Results from Organophospahtes and Autism in Mice

Posted on January 11, 2013 by researchinitiative

Decreased Reelin Expression and Organophosphate Pesticide Exposure Alters Mouse Behavior and Brain Morphology. http://www.ncbi.nlm.nih.gov/pubmed/23298182 Genetic and environmental factors are both likely to contribute to neurodevelopmental disorders, including autism spectrum disorders. In this study, we examined the combinatorial effect of two … Continue reading →

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Obesity, Mothers and Vitamin D

Posted on January 8, 2013 by researchinitiative

Vitamin D levels in umbilical cord blood found to be lower if mother is obese http://www.northwestern.edu/newscenter/stories/2013/01/obese-moms-risk-having-babies-with-low-vitamin-d_mobile.html By Erin White CHICAGO — Women who are obese at the start of their pregnancy may be passing on insufficient levels of vitamin D … Continue reading →

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