Tag Archives: schizophrenia

Schizophrenia – The Dual Hit Model

Neurodevelopmental Animal Models Reveal the Convergent Role of Neurotransmitter Systems, Inflammation, and Oxidative Stress as Biomarkers of Schizophrenia: Implications for Novel Drug Development. http://www.ncbi.nlm.nih.gov/pubmed/25794269 Abstract Schizophrenia is a life altering disease with a complex etiology and pathophysiology, and although antipsychotics … Continue reading

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Inflammatory Cytokines and Autism : A Relationship

Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: a preliminary report. http://www.ncbi.nlm.nih.gov/pubmed/23353117 Department of Psychiatry and Behavioral Sciences, Emory University, USA. Abstract 22q11.2 deletion syndrome (22q11DS) is a genetic disorder that conveys a significant risk … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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Maternal Inflammation – Significant Role in Autism II

Prenatal inflammation linked to autism risk http://www.niehs.nih.gov/news/newsroom/releases/2013/january24/index.cfm Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the … Continue reading

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Maternal Infection, a Mouse and Autism.

Aberrant Cerebellar Neurotrophin-3 Expression Induced by Lipopolysaccharide Exposure During Brain Development. http://www.ncbi.nlm.nih.gov/pubmed/23319369 Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. Abstract Autism is a developmental disorder affecting communication, social interaction, motor skills, … Continue reading

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Risk Gene for Alzheimer’s at Birth – Autism Implications.

Risk Genes for Alzheimer’s and Mental Illness Linked to Brain Changes at Birth http://www.sciencedaily.com/releases/2013/01/130102205459.htm Jan. 2, 2013 — Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer’s disease, schizophrenia, and autism … Continue reading

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Valproic Acid and Schizophrenia in Mice

Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice. http://www.ncbi.nlm.nih.gov/pubmed/23272119 Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada. Abstract BACKGROUND: Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility … Continue reading

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Gene Expression in Schizophrenia – Immune Pathways

Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells. http://www.ncbi.nlm.nih.gov/pubmed/23218666 Schizophrenia Research Institute, Sydney, NSW, Australia; Abstract Peripheral blood mononuclear cells (PBMCs) represent an accessible tissue source for gene expression profiling in schizophrenia that could provide … Continue reading

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Schizophrenia and the Immune System – Atopic Disorders

Schizophrenia in patients with atopic disorders with particular emphasis on asthma: a Danish population-based study. http://www.ncbi.nlm.nih.gov/pubmed/22391212 OBJECTIVE: Autoimmune diseases and infections have been associated with an increased risk of schizophrenia that could be rooted in inflammatory mechanisms. However, other diseases … Continue reading

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Top 40 Research Articles of 2012 – Autism

Top 40 Research Articles – ( 40 / 350) The research that asdresearchinitiative believes has contributed greatly to our understanding of ASD and most significantly the care of ASD children. 2012 may be seen by future generations as a breakthrough … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Fragile X, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 3 Comments