Tag Archives: NFkB

Diabetes Type 1 , Bacteria and Autism

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study http://www.biomedcentral.com/1741-7015/11/46/abstract Background A recent study using a rat model found significant differences at the time of diabetes onset in the bacterial communities responsible … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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Maternal Inflammation – Significant Role in Autism II

Prenatal inflammation linked to autism risk http://www.niehs.nih.gov/news/newsroom/releases/2013/january24/index.cfm Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the … Continue reading

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Maternal Inflammation – Significant Role in Autism

Elevated maternal C-reactive protein and autism in a national birth cohort. http://www.ncbi.nlm.nih.gov/pubmed/23337946 1] Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY, USA [2] Department of Epidemiology, Columbia University Mailman School … Continue reading

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Converging Enivronment and Genetics – Key Signalling Pathways

Neuronal connectivity as a convergent target of gene-environment interactions that confer risk for Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/23269408 Department of Molecular Biosciences, University of California at Davis School of Veterinary Medicine Abstract Evidence implicates environmental factors in the pathogenesis of Autism … Continue reading

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Top 40 Research Articles of 2012 – Autism

Top 40 Research Articles – ( 40 / 350) The research that asdresearchinitiative believes has contributed greatly to our understanding of ASD and most significantly the care of ASD children. 2012 may be seen by future generations as a breakthrough … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Fragile X, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 3 Comments

Microglia , the brain and Autism – Immune System Connections.

Microglia in the Cerebral Cortex in Autism http://link.springer.com/article/10.1007/s10803-012-1513-0/fulltext.html Division of Biology, California Institute of Technology Comprehensive Autism Center Abstract We immunocytochemically identified microglia in fronto-insular (FI) and visual cortex (VC) in autopsy brains of well-phenotyped subjects with autism and matched … Continue reading

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Autism – Atopic Dermatitis – Immune System : A Striking Association

Mental health comorbidity in patients with atopic dermatitis. http://www.ncbi.nlm.nih.gov/pubmed/23245818 School of Medicine, Oregon Health and Science University, Portland, Ore. Abstract BACKGROUND: Recent data, primarily from Europe, suggest that children with atopic dermatitis (AD) might be at increased risk of mental … Continue reading

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Blood Signatures, Neurotrophins, the immune system and Autism.

Characteristics and Predictive Value of Blood Transcriptome Signature in Males with Autism Spectrum Disorders http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515554/#pone.0049475.s010   Autism Spectrum Disorders (ASD) is a spectrum of highly heritable neurodevelopmental disorders in which known mutations contribute to disease risk in 20% of cases. … Continue reading

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Brain, infection and TLR3

Brain displays an intrinsic mechanism for fighting infection http://newswire.rockefeller.edu/2012/11/16/brain-displays-an-intrinsic-mechanism-for-fighting-infection/ White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the … Continue reading

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