Tag Archives: childhood schizophrenia

Inflammatory Cytokines and Autism : A Relationship

Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: a preliminary report. http://www.ncbi.nlm.nih.gov/pubmed/23353117 Department of Psychiatry and Behavioral Sciences, Emory University, USA. Abstract 22q11.2 deletion syndrome (22q11DS) is a genetic disorder that conveys a significant risk … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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Maternal Infection, a Mouse and Autism.

Aberrant Cerebellar Neurotrophin-3 Expression Induced by Lipopolysaccharide Exposure During Brain Development. http://www.ncbi.nlm.nih.gov/pubmed/23319369 Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. Abstract Autism is a developmental disorder affecting communication, social interaction, motor skills, … Continue reading

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Risk Gene for Alzheimer’s at Birth – Autism Implications.

Risk Genes for Alzheimer’s and Mental Illness Linked to Brain Changes at Birth http://www.sciencedaily.com/releases/2013/01/130102205459.htm Jan. 2, 2013 — Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer’s disease, schizophrenia, and autism … Continue reading

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Valproic Acid and Schizophrenia in Mice

Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice. http://www.ncbi.nlm.nih.gov/pubmed/23272119 Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada. Abstract BACKGROUND: Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility … Continue reading

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Gene Expression – Bipolar Disorder – Immune System

Up-Regulation of NOTCH4 Gene Expression in Bipolar Disorder. http://www.ncbi.nlm.nih.gov/pubmed/23212060 Abstract OBJECTIVE Immunopathogenic mechanisms have been implicated in schizophrenia and bipolar disorder, and genome-wide association studies (GWAS) point to the major histocompatibility complex, a region that contains many immune-related genes. One … Continue reading

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Gene Expression in Schizophrenia – Immune Pathways

Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells. http://www.ncbi.nlm.nih.gov/pubmed/23218666 Schizophrenia Research Institute, Sydney, NSW, Australia; Abstract Peripheral blood mononuclear cells (PBMCs) represent an accessible tissue source for gene expression profiling in schizophrenia that could provide … Continue reading

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Schizophrenia and the Immune System – Atopic Disorders

Schizophrenia in patients with atopic disorders with particular emphasis on asthma: a Danish population-based study. http://www.ncbi.nlm.nih.gov/pubmed/22391212 OBJECTIVE: Autoimmune diseases and infections have been associated with an increased risk of schizophrenia that could be rooted in inflammatory mechanisms. However, other diseases … Continue reading

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Top 40 Research Articles of 2012 – Autism

Top 40 Research Articles – ( 40 / 350) The research that asdresearchinitiative believes has contributed greatly to our understanding of ASD and most significantly the care of ASD children. 2012 may be seen by future generations as a breakthrough … Continue reading

Posted in Allergy, Asthma, Autism, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Fragile X, General, Genetics, Gut, Immune System, Inflammation, Mice, Muscular Dystrophy, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 3 Comments

Helminths , Colitis and Autism

Probiotic Worm Treatment May Improve Symptoms of Colitis by Restoring Gut Bacteria to Healthy State http://www.sciencedaily.com/releases/2012/11/121115172030.htm ScienceDaily (Nov. 15, 2012) — A new study on monkeys with chronic diarrhea that were treated by microscopic parasite worm (helminth) eggs has provided … Continue reading

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