Category Archives: Schizophrenia

Maternal Immune Activation – IL-6 and Disruption of Brain Development in Autism

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia http://www.jneuroinflammation.com/content/11/1/183 Abstract Background Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia. While several proteins have been identified … Continue reading

Posted in Autism, Environment, Immune System, Inflammation, Physiology, Schizophrenia, Treatment | Leave a comment

Gut Microbes and Neuroscience – The Paradigm Shift

Gut microbes and the brain: paradigm shift in neuroscience. http://www.ncbi.nlm.nih.gov/pubmed/25392516 Abstract The discovery of the size and complexity of the human microbiome has resulted in an ongoing reevaluation of many concepts of health and disease, including diseases affecting the CNS. … Continue reading

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, Depression, diabetes, Environment, Epigenetics, Genetics, Gut, IBD, Immune System, Inflammation, Neurology, Parents, Physiology, Schizophrenia | Leave a comment

Schizophrenia and Bacteria – Toxoplasma gondii may account for as much as 21%

Estimating the population attributable fraction for schizophrenia when Toxoplasma gondii is assumed absent in human populations http://www.sciencedirect.com Highlights •There is evidence that Toxoplasma gondii may be a component cause of schizophrenia. We describe a new method for estimating the population … Continue reading

Posted in Autism, Bacteria, co-morbid, Schizophrenia | Leave a comment

Maternal Immune Activation and Molecular Cascade

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. http://www.ncbi.nlm.nih.gov/pubmed/25374324 Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia. While several proteins have been identified as having … Continue reading

Posted in Autism, co-morbid, Environment, Immune System, Inflammation, Schizophrenia, Treatment, Virus | Leave a comment

THC, Immune System and Immune Diseases – Multiple Sclerosis, Inflammatory Bowel Disease and Rheumatoid Arthritis

Adolescent exposure to THC may cause immune systems to go up in smoke http://www.faseb.org/ New research published in the Journal of Leukocyte Biology suggests that early exposure to marijuana can affect immune system development, leading to immune-related diseases in adulthood … Continue reading

Posted in Autism, bowel disease, co-morbid, Environment, Gut, IBD, Immune System, Inflammation, Mice, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Leaky Gut in Autoimmune Disease – New Research in MS

Intestinal barrier damage in multiple sclerosis http://www.lunduniversity.lu.se 04 September 2014 Researchers at Lund University in Sweden have published new research findings on the role of the intestinal barrier in the autoimmune disease multiple sclerosis (MS). Within medical science, it is … Continue reading

Posted in Autism, Bacteria, bowel disease, co-morbid, Environment, Gut, IBD, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Toxins, Treatment | Leave a comment

mGlu2 – A Molecular Signature – Stress, Anxiety, Depression and Autism ?

Research hints at why stress is more devastating for some http://newswire.rockefeller.edu Some people take stress in stride; others are done in by it. New research at Rockefeller University has identified the molecular mechanisms of this so-called stress gap in mice … Continue reading

Posted in Autism, co-morbid, Depression, Neurology, Physiology, Schizophrenia | Leave a comment

Gene x Environment in Pediatric Crohn’s Disease II

Two-stage Genome-wide Methylation Profiling in Childhood-onset Crohn’s Disease Implicates Epigenetic Alterations at the VMP1/MIR21 and HLA Loci http://journals.lww.com Background: As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We … Continue reading

Posted in Allergy, Asthma, Autism, bowel disease, co-morbid, diabetes, Environment, Immune System, Inflammation, Schizophrenia, Treatment | Leave a comment

Autism , ADHD and the link to Allergy – Significant Higher Risk

Autistic spectrum disorder, attention deficit hyperactivity disorder, and allergy: Is there a link? A nationwide study http://www.sciencedirect.com/science/article/pii/S1750946714001664 Highlights Children with ADHD or ASD had an increased risk of allergic comorbidities. Children with both ADHD and ASD had the highest risk … Continue reading

Posted in Allergy, Asthma, Autism, bowel disease, co-morbid, Depression, diabetes, Environment, Epidemiology, Epigenetics, epilepsy, Gut, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment, Virus | 2 Comments

Vagus Nerve and Autism, Epilepsy, Depression and Schizophrenia

Vagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex. http://www.ncbi.nlm.nih.gov/pubmed/25128387 Abstract The ratio between synaptic inhibition and excitation (sI/E) is a critical factor in the pathophysiology of neuropsychiatric disease. We recently … Continue reading

Posted in Autism, co-morbid, Depression, Environment, Schizophrenia, Treatment | Leave a comment