Category Archives: Inflammation

The Gut, Microbes and MS

Changes Uncovered in the Gut Bacteria of Patients with Multiple Sclerosis http://www.brighamandwomens.org A connection between the bacteria living in the gut and immunological disorders such as multiple sclerosis have long been suspected, but for the first time, researchers have detected … Continue reading

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Immune System, Epilepsy and the Eye

Immune response in the eye following epileptic seizures http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0618-3   Abstract Background Epileptic seizures are associated with an immune response in the brain. However, it is not known whether it can extend to remote areas of the brain, such as … Continue reading

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Hygiene Hypothesis and The Gut.

The gut microbiomes of infants have an impact on autoimmunity http://www.aalto.fi/en/current/news/2016-04-28-006/ Exposure to pathogens early in life is beneficial to the education and development of the human immune system. Over the past few decades, the healthcare community has observed an … Continue reading

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, diabetes, Environment, Epigenetics, Genetics, Gut, IBD, Immune System, Inflammation, Treatment | Leave a comment

Environment x Genes – Fungicides and Autism

Could a new class of fungicides play a role in autism, neurodegenerative diseases? http://news.unchealthcare.org/news/2016/march/could-a-new-class-of-fungicides-play-a-role-in-autism-neurodegenerative-diseases A new UNC School of Medicine study shows how chemicals designed to protect crops can cause gene expression changes in mouse brain cells that look strikingly … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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Immune Response and Complement system play a Major role in Epilepsy

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading

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Inflammatory Pathways in Epilepsy

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/26877106 Abstract BACKGROUND: Accumulating evidence suggests a role for inflammation in the pathophysiology of epilepsy. METHODS: We performed a systematic review and meta-analysis of studies that investigated inflammatory mediators in … Continue reading

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Breakthrough – Autism, Immune Cells and Pruning

The Brain’s Gardeners: Immune Cells ‘Prune’ Connections Between Neurons https://www.urmc.rochester.edu A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring … Continue reading

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Maternal Care – Key to Autism

Obesity, Diabetes in Mom Increases Risk of Autism in Child http://www.jhsph.edu/news/news-releases/2016/obesity-diabetes-in-mom-increases-risk-of-autism-in-child.html New study offers new evidence that autism spectrum disorder risks may begin in utero Children born to obese women with diabetes are more than four times as likely to … Continue reading

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