Category Archives: Autism

Neuropathology of Seizures in Autism

Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder. http://www.ncbi.nlm.nih.gov/pubmed/27242398 Abstract This manuscript reviews biological abnormalities shared by autism spectrum disorder (ASD) and epilepsy. Two neuropathological findings are shared by ASD and epilepsy: abnormalities in minicolumn architecture and γ-aminobutyric acid (GABA) … Continue reading

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Immune System, Epilepsy and the Eye

Immune response in the eye following epileptic seizures http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0618-3   Abstract Background Epileptic seizures are associated with an immune response in the brain. However, it is not known whether it can extend to remote areas of the brain, such as … Continue reading

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Hygiene Hypothesis and The Gut.

The gut microbiomes of infants have an impact on autoimmunity http://www.aalto.fi/en/current/news/2016-04-28-006/ Exposure to pathogens early in life is beneficial to the education and development of the human immune system. Over the past few decades, the healthcare community has observed an … Continue reading

Posted in Allergy, Asthma, Autism, Bacteria, bowel disease, co-morbid, diabetes, Environment, Epigenetics, Genetics, Gut, IBD, Immune System, Inflammation, Treatment | Leave a comment

Chronic Lack of Sleep – Linked to Neurological Damage – Implications for Autism ?

 Insomnia Linked to Damage in Brain Communication Networks https://www2.rsna.org At A Glance Twenty-three insomnia patients and 30 healthy controls were examined with diffusion tensor imaging and given questionnaires to evaluate mental status and sleep patterns. Compared to the healthy controls, … Continue reading

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Environment x Genes – Fungicides and Autism

Could a new class of fungicides play a role in autism, neurodegenerative diseases? http://news.unchealthcare.org/news/2016/march/could-a-new-class-of-fungicides-play-a-role-in-autism-neurodegenerative-diseases A new UNC School of Medicine study shows how chemicals designed to protect crops can cause gene expression changes in mouse brain cells that look strikingly … Continue reading

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2016 CDC Autism Prevalence – 1 in 68

U.S. Autism Rate Unchanged in New CDC Report http://www.jhsph.edu Researchers say it’s too early to tell if rate has stabilized Researchers at the Johns Hopkins Bloomberg School of Public Health contributed to a new U.S. Centers for Disease Control and … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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New Shift in Understanding – We are all Autism

Autism genes are in all of us, new research reveals http://www.bristol.ac.uk/news/2016/march/autism-genetics-population.html New light has been shed on the genetic relationship between autistic spectrum disorders (ASD) and ASD-related traits in the wider population, by a team of international researchers including academics … Continue reading

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Immune Response and Complement system play a Major role in Epilepsy

Identification of novel gene and pathway targets for human epilepsy treatment. http://www.ncbi.nlm.nih.gov/pubmed/26742644  Abstract BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile … Continue reading

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