Search Results for: inflammation

Allergy, Inflammation and Autism

Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders Free Full Paper http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931610/ Abstract Autism spectrum disorders (ASDs) affect as many as 1 in 45 children and are characterized by deficits in sociability and communication, … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Microglia, Inflammation, the Immune System, Cerebral Palsy and Autism

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. http://www.ncbi.nlm.nih.gov/pubmed/27004516  Abstract BACKGROUND: Microglial cells have been implicated in neuroinflammation-mediated injury in the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism. Pro-inflammatory activation … Continue reading

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A Mother’s Inflammation and Autism

How severe maternal inflammation can lead to autism-like behavior http://news.mit.edu/2016/maternal-inflammation-autism-behavior-0128 Immune molecules in infected mothers tied to brain and behavior abnormalities in offspring.   Anne Trafton | MIT News Office January 28, 2016   In 2010, a large study in … Continue reading

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Inflammation Crucial in Disease – Implications for Autism

Controlling inflammation to reduce chronic disease risk http://www.alphagalileo.org 07 August 2015 ILSI Europe An unresolved inflammatory response is likely to be involved from the early stages of disease development. Controlling inflammation is crucial to human health and a key future … Continue reading

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Chronic Inflammation – Inflammatory Bowel Disease – Hippocampal Neurogenesis

Chronic intestinal inflammation alters hippocampal neurogenesis http://www.jneuroinflammation.com/content/12/1/65/abstract Background Adult neurogenesis in the subgranular zone of the hippocampus is involved in learning, memory, and mood control. Decreased hippocampal neurogenesis elicits significant behavioral changes, including cognitive impairment and depression. Inflammatory bowel disease … Continue reading

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Endotoxins / Inflammation challenge – Social Cognition and Autism

Inflammation impairs social cognitive processing: A randomized controlled trial of endotoxin. http://www.ncbi.nlm.nih.gov/pubmed/25770082 Abstract Neuropsychiatric disorders (e.g., autism, schizophrenia) are partially characterized by social cognitive deficits, including impairments in the ability to perceive others’ emotional states, which is an aspect of … Continue reading

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Brain Inflammation and Depression – 30% increase

New biological evidence reveals link between brain inflammation and major depression http://www.camh.ca TORONTO (Jan. 28, 2015) – A new study by the Centre for Addiction and Mental Health (CAMH) found that the measure of brain inflammation in people who were … Continue reading

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Brain Inflammation – A Hallmark of Autism

Brain Inflammation A Hallmark Of Autism, Large-Scale Analysis Shows http://www.hopkinsmedicine.org While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. … Continue reading

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Neuroinflammation and Autism – Imbalance in GABAergic and glutamatergic synapses as a consequence of neuroinflammation.

GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders  http://www.jneuroinflammation.com/content/11/1/189 Background Autism spectrum disorder (ASD) is characterized by three core behavioral domains: social deficits, impaired communication, and repetitive behaviors. Glutamatergic/GABAergic imbalance has been found in various preclinical models of … Continue reading

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