Search Results for: environment

Environment x Genes – Fungicides and Autism

Could a new class of fungicides play a role in autism, neurodegenerative diseases? http://news.unchealthcare.org/news/2016/march/could-a-new-class-of-fungicides-play-a-role-in-autism-neurodegenerative-diseases A new UNC School of Medicine study shows how chemicals designed to protect crops can cause gene expression changes in mouse brain cells that look strikingly … Continue reading

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Environmental Enrichment as a Treatment for Early Life Inflammation

Environmental enrichment rescues the effects of early life inflammation on markers of synaptic transmission and plasticity. http://www.ncbi.nlm.nih.gov/pubmed/27002704  Abstract Environmental enrichment (EE) has been successful at rescuing the brain from a variety of early-life psychogenic stressors. However, its ability to reverse … Continue reading

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Environment as a driver of ASD

Annual Research Review: The role of the environment in the developmental psychopathology of autism spectrum condition.  http://www.ncbi.nlm.nih.gov/pubmed/26782158 Abstract BACKGROUND: Although autism spectrum condition (ASC) is strongly genetic in origin, accumulating evidence points to the critical roles of various environmental influences … Continue reading

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Toxicant Exposure and Autism – The Maternal Environment

The plausibility of maternal toxicant exposure and nutritional status as contributing factors to the risk of autism spectrum disorders. http://www.ncbi.nlm.nih.gov/pubmed/26613405 Abstract Recent research suggests the maternal environment may be especially important for the risk of developing autism spectrum disorders (ASD). … Continue reading

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Autism more prevalent in Urban environments – Denmark

Urban-rural differences in incidence rates of psychiatric disorders in Denmark. http://www.ncbi.nlm.nih.gov/pubmed/26678865 Abstract Background People born in densely populated areas have a higher risk of developing schizophrenia, bipolar disorder and autism. Aims The purpose of this study was to investigate whether … Continue reading

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Autism – Environment for Boys , Genetics for Girls

Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins. http://www.ncbi.nlm.nih.gov/pubmed/25973164 BACKGROUND: Autism spectrum disorders (ASDs) are more prevalent in males, suggesting a multiple threshold liability model in which females are, on … Continue reading

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Genes / Environment – Autism Twin Study

The Relationship Among Genetic Heritability, Environmental Effects, and Autism Spectrum Disorders: 37 Pairs of Ascertained Twin Study. Abstract Autism spectrum disorders (ASD) comprise a heterogeneous group of neurodevelopmental disorders that have strong heritability. To better understand the heritable factors in … Continue reading

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Environment not Genes – Immune System Variation

Environment, not genes, plays starring role in human immune variation, study finds http://med.stanford.edu Improving gene-sequencing technologies have focused immunologists’ attention on the role of genes in diseases. But it appears the environment is an even greater factor in the human … Continue reading

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Environment and Epigenetic changes – Project Ice Storm

Prenatal maternal stress exposure to natural disasters predicts epigenetic profile of offspring http://www.douglas.qc.ca/news/1284?locale=en The number of days an expectant mother was deprived of electricity during Quebec’s Ice Storm (1998) predicts the epigenetic profile of her child, a new study finds. … Continue reading

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Gene x Environment in Pediatric Crohn’s Disease II

Two-stage Genome-wide Methylation Profiling in Childhood-onset Crohn’s Disease Implicates Epigenetic Alterations at the VMP1/MIR21 and HLA Loci http://journals.lww.com Background: As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We … Continue reading

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