Search Results for: MHC

Immune Protiens (MHC1) – Autism, Alzheimer’s and Diabetes

Immune proteins moonlight to regulate brain-cell connections  http://www.princeton.edu by Morgan Kelly, Office of Communications When it comes to the brain, “more is better” seems like an obvious assumption. But in the case of synapses, which are the connections between brain … Continue reading

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Major Histocompatibility Complex (MHC) – Autism and Schizophrenia

Does Immune Dysfunction Contribute to Schizophrenia? Genetic Findings from New Study http://www.sciencedaily.com/releases/2012/10/121010102033.htm ScienceDaily (Oct. 10, 2012) — A new study reinforces the finding that a region of the genome involved in immune system function, called the major histocompatibility complex (MHC), … Continue reading

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Gene x Environment in Pediatric Crohn’s Disease II

Two-stage Genome-wide Methylation Profiling in Childhood-onset Crohn’s Disease Implicates Epigenetic Alterations at the VMP1/MIR21 and HLA Loci http://journals.lww.com Background: As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We … Continue reading

Posted in Allergy, Asthma, Autism, bowel disease, co-morbid, diabetes, Environment, Immune System, Inflammation, Schizophrenia, Treatment | Leave a comment

Maternal Viral Infection and Autism – Disruption of Neural Development

UC Davis researchers find how viral infection disrupts neural development in offspring, increasing risk of autism http://www.ucdmc.ucdavis.edu/publish/news/newsroom/8208 (SACRAMENTO, Calif.) — Activating a mother’s immune system during her pregnancy disrupts the development of neural cells in the brain of her offspring … Continue reading

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eTAC – New Approaches to Autoimmune Disease

Autoimmune Disease Strategy Emerges from Immune Cell Discovery UCSF Experiments Halt Pancreas Destruction in Mouse Model of Diabetes http://www.ucsf.edu/news/2013/09/108746/autoimmune-disease-strategy-emerges-immune-cell-discovery Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking … Continue reading

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Immune and Autoimmune Phenomena in ASD research

Immunological and autoimmune considerations of Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/23867105 Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired … Continue reading

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Is Asthma the opposite of Autoimmune Diseases – Implications for Autism ?

Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. http://www.ncbi.nlm.nih.gov/pubmed/22694930 Abstract BACKGROUND: Genome-wide association studies (GWASs) of asthma have consistently implicated the ORM1-like 3 and gasdermin B (ORMDL3-GSDMB), IL33, IL-1 receptor-like 1 and IL-18 receptor 1 (IL1RL1-IL18R1), … Continue reading

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Schizophrenia and Lead – Implications for Autism ?

Lead acts to trigger schizophrenia http://www.mailman.columbia.edu/ Behavioral and MRI study in mice points to a synergistic relationship between lead exposure and schizophrenia gene Mice engineered with a human gene for schizophrenia and exposed to lead during early life exhibited behaviors … Continue reading

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Commensal Bacteria – Loss of ILC Function and Disease – Implications for Autism ?

Penn Study Shows How Immune System Peacefully Co-exists with “Good” Bacteria http://www.uphs.upenn.edu/news/News_Releases/2013/05/sonnenberg/ Understanding How This Immunological Truce Is Kept Suggests New Ways to Fight Inflammatory Diseases PHILADELPHIA — The human gut is loaded with commensal bacteria – “good” microbes that, … Continue reading

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Major Histocompatibility Complex and Epilepsy – Autism Implications ?

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions http://www.jneuroinflammation.com/content/10/1/12/abstract Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands Full PDF at link Abstract (provisional) The expression of the major … Continue reading

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