Personalized medicine: Time for one-person trials
Nicholas J. Schork
Precision medicine requires a different type of clinical trial that focuses on individual, not average, responses to therapy, says Nicholas J. Schork.
“Every day, millions of people are taking medications that will not help them. The top ten highest-grossing drugs in the United States help between 1 in 25 and 1 in 4 of the people who take them (see ‘Imprecision medicine’). For some drugs, such as statins — routinely used to lower cholesterol — as few as 1 in 50 may benefit1. There are even drugs that are harmful to certain ethnic groups because of the bias towards white Western participants in classical clinical trials2.”
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A fascinating and insightful look at modern pharmacological based medicine. The implications in how children and young adults with Autism and other mental health issues are dealt with should be in the back of everyone’s mind that reads this article in full.