Daily Archives: November 27, 2014

Immune Insults in Autism – A New Subset ( ASD -Inflammatory Subtype)

Cytokine profiles by peripheral blood monocytes are associated with changes in behavioral symptoms following immune insults in a subset of ASD subjects: an inflammatory subtype? http://www.jneuroinflammation.com/content/11/1/187 Abstract Background Some children with autism spectrum disorders (ASD) are characterized by fluctuating behavioral … Continue reading

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Maternal Immune Activation – IL-6 and Disruption of Brain Development in Autism

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia http://www.jneuroinflammation.com/content/11/1/183 Abstract Background Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia. While several proteins have been identified … Continue reading

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Neuroinflammation and Autism – Imbalance in GABAergic and glutamatergic synapses as a consequence of neuroinflammation.

GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders ¬†http://www.jneuroinflammation.com/content/11/1/189 Background Autism spectrum disorder (ASD) is characterized by three core behavioral domains: social deficits, impaired communication, and repetitive behaviors. Glutamatergic/GABAergic imbalance has been found in various preclinical models of … Continue reading

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