Monthly Archives: August 2014

Muscular Dystrophy and Autism – New Research focus on Females

Diagnostic and clinical characteristics of early-manifesting females with Duchenne or Becker muscular dystrophy. http://www.ncbi.nlm.nih.gov/pubmed/25125379 Abstract Manifestations of Duchenne and Becker muscular dystrophy (DBMD) are present in up to 40% of heterozygous females, but there are few reports of females who … Continue reading

Posted in Autism, co-morbid, Inflammation, Muscular Dystrophy, Neurology | Leave a comment

Vagus Nerve and Autism, Epilepsy, Depression and Schizophrenia

Vagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex. http://www.ncbi.nlm.nih.gov/pubmed/25128387 Abstract The ratio between synaptic inhibition and excitation (sI/E) is a critical factor in the pathophysiology of neuropsychiatric disease. We recently … Continue reading

Posted in Autism, co-morbid, Depression, Environment, Schizophrenia, Treatment | Leave a comment

The dynamic interplay between environmental and genetic factors – A Review

Epigenetic mechanisms in autism spectrum disorder. http://www.ncbi.nlm.nih.gov/pubmed/25131546 Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions, language deficits, as well as restrictive or repetitive behaviors. ASD is clinically heterogeneous with a complex etiopathogenesis which may … Continue reading

Posted in Environment, Epigenetics, Genetics, Neurology, Physiology, Treatment | Leave a comment

Gene x Environment – A Review

Gene × Environment interactions in autism spectrum disorders: role of epigenetic mechanisms. http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00053/full Full Paper at Link Abstract Several studies support currently the hypothesis that autism etiology is based on a polygenic and epistatic model. However, despite advances in epidemiological, molecular and … Continue reading

Posted in Autism, co-morbid, Environment, Genetics | Leave a comment

Alcohol Use Disorder and Risk for Autism – Increased Risk

Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders. http://www.ncbi.nlm.nih.gov/pubmed/25139954 Abstract Recent studies suggest de novo mutations may involve the pathogenesis of autism and attention-deficit/hyperactivity disorder (ADHD). Based on the evidence that excessive alcohol consumption … Continue reading

Posted in Autism, co-morbid, Environment, Genetics, Neurology, Physiology, Treatment | Leave a comment

Aspirin – More Effects on Inflammation

Aspirin, Take Two  http://health.ucsd.edu White blood cell research shows how causing and conquering inflammation are inextricably linked  Hugely popular non-steroidal anti-inflammation drugs like aspirin, naproxen (marketed as Aleve) and ibuprofen (Advil, Motrin) all work by inhibiting or killing an enzyme … Continue reading

Posted in Autism, co-morbid, Environment, Immune System, Inflammation, Treatment | Leave a comment

Genes x Environment – Stress and the Hippocampus – Implications for Autism

Our genes determine the traces that stress leaves behind on our brains. http://www.meduniwien.ac.at (Vienna, 18th August 2014) Our individual genetic make-up determines the effect that stress has on our emotional centres. These are the findings of a group of researchers … Continue reading

Posted in Uncategorized | Leave a comment

Immune System, IL-6 , Mental Illness, Coronary Heart Disease and Diabetes

Mind and body: Scientists identify immune system link to mental illness http://www.cam.ac.uk Children with high everyday levels of a protein released into the blood in response to infection are at greater risk of developing depression and psychosis in adulthood, according … Continue reading

Posted in Autism, co-morbid, Environment, Gut, Immune System, Inflammation, influenza, Mice, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Children’s Health Influenced Before Conception

Message to parents: babies don’t “start from scratch” http://www.adelaide.edu.au/news/news72402.htm   There’s now overwhelming evidence that a child’s future health is influenced by more than just their parents’ genetic material, and that children born of unhealthy parents will already be pre-programmed … Continue reading

Posted in Autism, co-morbid, Environment, Immune System | Leave a comment

Early Antibiotic Exposures, Critical Windows and Lifelong Effect

Early Antibiotic Exposure Leads to Lifelong Metabolic Disturbances in Mice http://www.med.nyu.edu/ New study suggests bacteria help program metabolic development A new study published today in Cell suggests that antibiotic exposure during a critical window of early development disrupts the bacterial … Continue reading

Posted in Autism, co-morbid, diabetes, Environment, Gut, Immune System, Inflammation, Mice, Parents, Treatment | Leave a comment