Co-occurrence of Autism and Asthma in a Nationally-Representative Sample of Children in the United States.
Few large epidemiological studies have examined the co-occurrence of autism and asthma.
We performed a cross-sectional study to examine this association using the 2007 National Survey of Children’s Health dataset (n = 77,951).
We controlled for confounders and tested for autism-secondhand smoke interaction.
Prevalence of asthma and autism were 14.5 % (n = 11,335) and 1.81 % (n = 1,412) respectively.
Unadjusted odds ratio (OR) for asthma among autistic children was 1.35 (95 % CI 1.18-1.55).
Adjusting for covariates (age, gender, body mass index, race, brain injury, secondhand smoke and socio-economic status) attenuated the OR to 1.19 (95 % CI 1.03-1.36).
Autism-secondhand smoke interaction was insignificant (p = 0.38). Asthma is approximately 35 % more common in autistic children; screening may be an efficient approach to reduce risk of morbidity due to asthma.
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