Daily Archives: January 31, 2014

Familial Transmission of ASD – Mothers with ADHD

Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders. http://www.ncbi.nlm.nih.gov/pubmed/24444366 Abstract BACKGROUND: To determine whether familial transmission is shared between autism spectrum disorders and attention-deficit/hyperactivity disorder, we assessed the prevalence, rates of comorbidity, and familial transmission of both disorders in … Continue reading

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Intellectual Disability in Autism – Distinct Therapeutic Strategies

Long-Term Memory Deficits are Associated with Elevated Synaptic ERK1/2 Activation and Reversed by mGluR5 Antagonism in an Animal Model of Autism. http://www.ncbi.nlm.nih.gov/pubmed/24448645 Abstract A significant proportion of patients with autism exhibit some degree of intellectual disability. The BTBR T+ Itpr3tf/J … Continue reading

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White Matter Tracts and ASD – MIT New Findings

Differences in the right inferior longitudinal fasciculus but no general disruption of white matter tracts in children with autism spectrum disorder. http://www.ncbi.nlm.nih.gov/pubmed/24449864 Abstract One of the most widely cited features of the neural phenotype of autism is reduced “integrity” of … Continue reading

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Household Pesticides and Autism

Autism spectrum disorder, flea and tick medication, and adjustments for exposure misclassification: the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. http://www.ncbi.nlm.nih.gov/pubmed/24456651 BACKGROUND: The environmental contribution to autism spectrum disorders (ASD) is largely unknown, but household pesticides are … Continue reading

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Lipopolysaccharide, Propionic Acid and ASD

Pre- and neonatal exposure to lipopolysaccharide or the enteric metabolite, propionic Acid, alters development and behavior in adolescent rats in a sexually dimorphic manner. http://www.ncbi.nlm.nih.gov/pubmed/24466331 Abstract Alterations in the composition of the gut microbiome and/or immune system function may have … Continue reading

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