Inflammation Marker Higher in Kids with Asthma, Depression
Published: Aug 9, 2013 | Updated: Aug 9, 2013
Children and adolescents with coexisting asthma and depression tended to have high levels of the inflammatory marker C-reactive protein (CRP), researchers found.
After controlling for variables including other illnesses and socioeconomic status, the presence of both asthma and depression was associated with a sevenfold greater risk of having levels of CRP above 2 mg/L (OR 7.02, 95% CI 1.13-43.48, P<0.05), according to Lilly Shanahan, PhD, of the University of North Carolina in Chapel Hill, and colleagues.
And for children with both conditions, the likelihood of having CRP levels above 3 mg/L rose tenfold (OR 10.04, 95% CI 1.42-70.96, P<0.05), the researchers reported online in the Journal of Pediatrics.
Measurement of CRP is a common way of estimating risk for chronic inflammatory disease in adults, with levels above 3 mg/L often being used as a cutoff.
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