Daily Archives: June 12, 2013

Risperidone : Permanent effects – Hyperactivity

Adult rats treated with risperidone during development are hyperactive. http://www.ncbi.nlm.nih.gov/pubmed/23750695 Abstract Risperidone is an antipsychotic drug approved for use in children, but little is known about the long-term effects of early-life risperidone treatment. In animals, prolonged risperidone administration during development … Continue reading

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Reelin, Ketamine, Autism

Reelin, an extracellular matrix protein linked to early onset psychiatric diseases, drives postnatal development of the prefrontal cortex via GluN2B-NMDARs and the mTOR pathway. http://www.ncbi.nlm.nih.gov/pubmed/23752244 Abstract Defective brain extracellular matrix (ECM) is a factor of vulnerability in various psychiatric diseases … Continue reading

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Ketogenic Diet in Autism and Core Symptoms

Ketogenic Diet Improves Core Symptoms of Autism in BTBR Mice. http://www.ncbi.nlm.nih.gov/pubmed/23755170 Abstract AUTISM SPECTRUM DISORDERS SHARE THREE CORE SYMPTOMS: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate. Seizures are a common comorbidity, and … Continue reading

Posted in Autism, co-morbid, Environment, epilepsy, Immune System, Inflammation, Mice, Neurology, Physiology, Treatment | Leave a comment

Autoimmune Disease and the Gut : New Insights

GI tract bacteria may protect against autoimmune disease http://www.ufz.de/index.php?en=31258 Researchers show that altering gut microbes protects against disease, supporting the ‘hygiene hypothesis’ Toronto. Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in … Continue reading

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Inflammatory Bowel Disease and Female Mice

Females fend off gut diseases http://msutoday.msu.edu/news/2013/females-fend-off-gut-diseases/ At least among mice, females have innate protection from certain digestive conditions, according to a new Michigan State University study. While it’s tricky to draw conclusions for human health, the findings could eventually help … Continue reading

Posted in Autism, co-morbid, Gut, Immune System, Inflammation, Mice, Neurology, Physiology, Treatment | Leave a comment