Daily Archives: April 7, 2013

Aspirin (COX-2) : Implications for Schizophrenia, Depression and Autism ?

Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness. http://www.ncbi.nlm.nih.gov/pubmed/23506529 Abstract There is compelling evidence to support an aetiological role for inflammation, oxidative and nitrosative stress (O&NS), and mitochondrial dysfunction in the pathophysiology of major neuropsychiatric … Continue reading

Posted in Autism, Environment, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Celecoxib (COX-2) treatment : Implications for Schizophrenia and Autism ?

Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide http://www.jneuroinflammation.com/content/10/1/45/abstract Background Cyclooxygenase-2 (COX-2) is induced in inflammatory cells in response to cytokines and pro-inflammatory molecules, suggesting that COX-2 has a role in … Continue reading

Posted in Autism, co-morbid, Immune System, Inflammation, Mice, Physiology, Schizophrenia, Treatment | 2 Comments