Autism and Bowel Disorders

Autism Spectrum Disorders in Children with Functional Defecation Disorders.

Department of Pediatric Gastroenterology and Nutrition, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands



To prospectively assess the prevalence of autism spectrum disorder (ASD) symptoms in children presenting with functional defecation disorders.


Children (age 4-12 years) with functional constipation or functional non-retentive fecal incontinence according to the Rome III criteria referred to a specialized outpatient clinic were included.

Parents completed 2 validated ASD screening questionnaires about their child; the Social Responsiveness Scale (SRS) and the Social Communication Questionnaire-Lifetime (SCQ-L). A total SRS score of ≥51 is a strong indicator for the presence of ASD. On the SCQ-L, a score of ≥15 is suggestive for ASD.


In total, 242 patients (130 males, median age 7.9 years) were included. Of these, 91% were diagnosed with functional constipation and 9% with functional non-retentive fecal incontinence.

Thirteen children (5.4%) had previously been diagnosed with ASD.

Twenty-six children (11%) had both SRS and SCQ-L scores at or above cutoff points, strongly suggestive for the presence of ASD.

Solely high SRS were present in 42 children (17%), whereas two children (1%) only had high SCQ-L scores.

Altogether, 29% had ASD symptoms, indicated by SRS and/or SCQ-L scores at or above the cutoff values. These children were older than children without ASD symptoms and presented with a longer duration of symptoms.


A substantial number of children (29%) presenting with a functional defecation disorder at a tertiary hospital has concomitant ASD symptoms. Clinicians should be aware of ASD symptoms in children with functional defecation disorders.

This entry was posted in Autism, co-morbid, Gut, Physiology, Treatment. Bookmark the permalink.

One Response to Autism and Bowel Disorders

  1. Pingback: Autism and Bowel Disorders | asdresearchinitiative | Signs And Symptoms For Autism

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s