Daily Archives: March 15, 2013

The Placenta, OGT, Immune System and Autism

O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development. http://www.ncbi.nlm.nih.gov/pubmed/23487789 Abstract Maternal stress is a key risk factor for neurodevelopmental disorders, including schizophrenia and autism, which often exhibit a sex bias … Continue reading

Posted in Autism, Environment, Genetics, Gut, Immune System, Inflammation, Neurology, Physiology, Schizophrenia, Treatment | Leave a comment

Diabetes Type 1 , Bacteria and Autism

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study http://www.biomedcentral.com/1741-7015/11/46/abstract Background A recent study using a rat model found significant differences at the time of diabetes onset in the bacterial communities responsible … Continue reading

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Mental Health and the Gut

Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part II — contemporary contextual research http://www.gutpathogens.com/content/5/1/3/abstract Abstract (provisional) In recent years there has been a renewed interest concerning the ways in which the gastrointestinal tract — its functional … Continue reading

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Cytokines, the Immune System and Autism

Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder http://www.jneuroinflammation.com/content/10/1/38/abstract Abstract (provisional) Objective Converging lines of evidence point to the existence of immune dysfunction in autism spectrum disorder (ASD), which could directly affect several key neurodevelopmental processes. Previous … Continue reading

Posted in Allergy, Asthma, Autism, Environment, Immune System, Inflammation, Neurology, Physiology, Treatment | Leave a comment