Daily Archives: December 30, 2012

Valproic Acid and Schizophrenia in Mice

Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice. http://www.ncbi.nlm.nih.gov/pubmed/23272119 Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada. Abstract BACKGROUND: Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility … Continue reading

Posted in Autism, co-morbid, Depression, Environment, Neurology, Physiology, Schizophrenia, Treatment | Tagged , , , , | Leave a comment

An Inflexible Mouse – BTBR and BDNF – and the Gut.

Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+tf/J strain, a mouse model of autism. http://www.ncbi.nlm.nih.gov/pubmed/23270976 Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Viale Regina Elena, 299 I-00161 Rome, Italy. Abstract Autism is a … Continue reading

Posted in Autism, Environment, Epigenetics, Genetics, Gut, Immune System, Inflammation, Mice, Neurology, Physiology, Treatment | Tagged , , , , , , , , , , | Leave a comment