Daily Archives: December 8, 2012

Autism – It’s the Immune System – Genetic Pathways confirmation.

Combining Two Genome Analysis Approaches Supports Immune System Contribution to Autism http://www.sciencedaily.com/releases/2012/12/121206203417.htm ScienceDaily (Dec. 6, 2012) — Researchers using novel approaches and methodologies of identifying genes that contribute to the development of autism have found evidence that disturbances in several … Continue reading

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MTHFR, Spina Bifida , ADHD and Autism.

Folate Metabolism Gene 5,10-Methylenetetrahydrofolate Reductase (MTHFR) Is Associated with ADHD in Myelomeningocele Patients http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0051330 The objective of this study was to examine the relation between the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene and behaviors related to attention- deficit/hyperactivity disorder (ADHD) in … Continue reading

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Helminths – A randomised, double-blind, placebo-controlled trial.

Impact of Anthelminthic Treatment in Pregnancy and Childhood on Immunisations, Infections and Eczema in Childhood: A Randomised Controlled Trial http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050325?imageURI=info:doi/10.1371/journal.pone.0050325.t002 Background Helminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the … Continue reading

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Bacteria, Stress and Leaky Gut

Commensal Bacteria and MAMPs Are Necessary for Stress-Induced Increases in IL-1β and IL-18 but Not IL-6, IL-10 or MCP-1 http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0050636 Full Article at Link Regular interactions between commensal bacteria and the enteric mucosal immune environment are necessary for normal immunity. … Continue reading

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Amyotrophic Lateral Sclerosis, autism and inflammation

One gene predicts rapid ALS progression 80 percent of the time http://www.methodisthealth.com/body.cfm?xyzpdqabc=0&id=495&action=detail&ref=979 The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in … Continue reading

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Muscular Dystrophy and Autism – Genetic / Immune System Linkage ?

Another Muscular Dystrophy Mystery Solved; Scientists Inch Closer to a Therapy for Patients http://www.sciencedaily.com/releases/2012/12/121207161634.htm ScienceDaily (Dec. 7, 2012) — Approximately 250,000 people in the United States suffer from muscular dystrophy, which occurs when damaged muscle tissue is replaced with fibrous, … Continue reading

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MECP2 and the Immune System

MECP2 duplication affects immune system as well as brain development http://www.bcm.edu/news/item.cfm?newsID=6571 HOUSTON — (December 5, 2012) — In 1999, Dr. Huda Zoghbi and colleagues at Baylor College of Medicine identified the genetic cause of Rett syndrome (a neurological disorder that … Continue reading

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Genetic Adaptation , Mutation , Environmental Stress – Implications for Autism.

Gene network illuminates stress, mutation and adaptation responses http://www.bcm.edu/news/item.cfm?newsID=6572 HOUSTON — (December 6, 2012) — For much of her professional life, Dr. Susan Rosenberg has studied the puzzling response of bacteria to stress and the mutations that result. In the … Continue reading

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