Massive Trials to Test Inflammation Hypothesis
More than 20 years ago, cardiologist Paul Ridker of Brigham and Women’s Hospital began nurturing the idea that inflammation is deeply intertwined with cardiovascular disease. Ridker has never been able to prove that the body’s inflammatory response causes heart attacks—or that blocking it can save lives. But he has built his case bit by bit. Now, his theory is being put to the test in a pair of massive clinical trials, both of which he’s heading. One was launched last year by Novartis, and the other was announced last month by the U.S. National Heart, Lung, and Blood Institute.
Are researchers following the infammatory aspects of autism following a similar path ? The evidence is certainly robust enough to implicate an inflammatory process in a majority of ASD cases … but where will it lead us and will it take 20 years to unfold ?