Daily Archives: August 1, 2012

When big words meet – Psychoneuroimmunology meets Neuropsychopharmacology

Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. http://www.ncbi.nlm.nih.gov/pubmed/21918508 The potential contribution of chronic inflammation to the development of neuropsychiatric disorders such as major depression has received increasing attention. Elevated biomarkers of inflammation, including inflammatory cytokines … Continue reading

Posted in Autism, co-morbid, Depression, Gut, Immune System, Inflammation, Physiology, Treatment | Tagged , , , , , , , , | Leave a comment

Epigenetics and Twins – Autism

Twin differences – Emily Singer – SFARI http://sfari.org/news-and-opinion/blog/twin-differences “You might think that in the cramped quarters of the womb, twins would experience pretty much the same environment. But a new study, published 15 July in Genome Research, suggests otherwise. Identical … Continue reading

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Individual common variants exert weak effects on risk for Autism Spectrum Disorders.

Individual common variants exert weak effects on risk for Autism Spectrum Disorders. http://www.ncbi.nlm.nih.gov/pubmed/22843504 While it is apparent that rare variation can play an important role in the genetic architecture of autism spectrum disorders (ASD), the contribution of common variation to … Continue reading

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Prenatal Valproic acid Exposure – Autism

Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway. http://www.ncbi.nlm.nih.gov/pubmed/22841957 Autism is a spectrum of neurodevelopmental disorders characterized by social isolation and lack of interaction. … Continue reading

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Mother and Child – Autism – Immune Activation

Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development. http://www.ncbi.nlm.nih.gov/pubmed/22841693 Maternal infection is a risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ). Indeed, modeling this risk factor in mice through maternal immune … Continue reading

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